ArticlePloS one2019
Quantitative CT and pulmonary function in children with post-infectious bronchiolitis obliterans.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The trial behind it
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Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Therapeutic interventions and pulmonary function in pediatric patients with post-infectious bronchiolitis obliterans.World journal of clinical pediatrics · 2026Review
- Risk factors for bronchiolitis obliterans in children with community-acquired pneumonia and analysis of CT findings and clinical manifestations of pneumonia after the diagnosis of bronchiolitis obliterans.Annals of medicine · 2025Article
- Changes in lung function in children after pneumonia: a multicenter study.Italian journal of pediatrics · 2025Article
- Predicting pulmonary function using thoracic deformity parameters in early onset scoliosis patients.PloS one · 2025Article
- Postinfectious Bronchiolitis Obliterans in Children.Canadian respiratory journal · 2025Review
- Article
- Pulmonary Function in Post-Infectious Bronchiolitis Obliterans in Children: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2022Review
- Quantitative CT lung densitometry as an obstructive marker for the diagnosis of bronchiolitis obliterans in children.PloS one · 2022Article
- The lower respiratory airway wall in children in health and disease.ERJ open research · 2021Review
- Lung density analysis using quantitative computed tomography in children with pectus excavatum.Polish journal of radiology · 2021Article
- [Imaging of Acute Pulmonary and Airway Diseases in Children].Taehan Yongsang Uihakhoe chi · 2020Review
- Quantitative CT Analysis of Small Airway Remodeling in Patients with Chronic Obstructive Pulmonary Disease by a New Image Post-Processing System.International journal of chronic obstructive pulmonary diseaseArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the feasibility of CT-based quantitative airway and air-trapping measurements and to assess their correlation with pulmonary function in children with post-infectious bronchiolitis obliterans (PIBO). MATERIALS AND
methodsThis retrospective study approved by the institutional review board included chest CT scans and pulmonary function tests (PFT) completed between January 2005 and December 2016 in children diagnosed with PIBO. The quantitative analysis of segmental and subsegmental bronchi was performed on each chest CT scan, measuring the areas or diameters of lumens, walls, or the entire airway. The air-trapping volume (ATV), the volume of lung area exhibiting lower attenuation than the mean attenuation of normal and air-trapping areas, was also measured in each lobe. Comparison analyses between CT parameters and PFT results were performed with Pearson or Spearman correlation.
resultsIn total, 23 patients were enrolled (mean age 7.0 ± 3.3 years; range, 4-15 years). We successfully measured 89.6% of all segmental bronchi. In the airway analysis, wall area showed a negative correlation with forced expiratory volume in one second (FEV1) in the majority of the pulmonary lobes. Air-trapping analyses demonstrated that ATV was negatively correlated with FEV1 and positively correlated with reactance at 5 Hz.
conclusionQuantitative airway and air-trapping measurements from chest CT are feasible and correlate with pulmonary function in pediatric PIBO patients.
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