Trial reportJournal of psychiatric research2019
Cognitive functioning as a predictor of response to comprehensive cognitive remediation.
Trial report in Journal of psychiatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness, Core Elements, and Moderators of Response of Cognitive Remediation for Schizophrenia: A Systematic Review and Meta-analysis of Randomized Clinical Trials.JAMA psychiatry · 2021Pooled it
- Comparison of Black and White participants with severe mental illness in response to cognitive remediation as an augmentation of vocational rehabilitation.Schizophrenia research · 2023Trial
- Effectiveness of KarXT (xanomeline-trospium) for cognitive impairment in schizophrenia: post hoc analyses from a randomised, double-blind, placebo-controlled phase 2 study.Translational psychiatry · 2022Trial
- Sex differences in event-related potentials and their clinical predictive value in first-episode antipsychotic-naïve schizophrenia.European archives of psychiatry and clinical neuroscience · 2026Article
- Nanotechnology-Enhanced MicroRNAs for Improved Diagnosis and Treatment of Major Depressive Disorder: A Comprehensive Review.Molecular neurobiology · 2025Review
- Ecological virtual reality-based cognitive remediation among inpatients with schizophrenia: A pilot study.Schizophrenia research. Cognition · 2024Article
- Improving outcome of treatment-resistant schizophrenia: effects of cognitive remediation therapy.European archives of psychiatry and clinical neuroscience · 2024Article
- Eye movements as predictor of cognitive improvement after cognitive remediation therapy in patients with schizophrenia.Frontiers in psychiatry · 2024Article
- Moderators of metacognitive strategy training for executive functioning in early schizophrenia and psychosis risk.Schizophrenia research. Cognition · 2023Article
- Cognitive remediation in schizophrenia: What happens after 10 years?Schizophrenia research. Cognition · 2022Article
- Examining the association of life course neurocognitive ability with real-world functioning in schizophrenia-spectrum disorders.Schizophrenia research. Cognition · 2022Article
- Lifespan evolution of neurocognitive impairment in schizophrenia - A narrative review.Schizophrenia research. Cognition · 2022Review
- Predicting response to cognitive training for schizophrenia using results from two studies with different outcomes.Schizophrenia research · 2021Article
- Sex differences in association between cognitive impairment and clinical correlates in Chinese patients with first-episode drug-naïve schizophrenia.Annals of general psychiatry · 2021Article
- Aged rhesus monkeys: Cognitive performance categorizations and preclinical drug testing.Neuropharmacology · 2021Article
- α7 nicotinic acetylcholine receptors as therapeutic targets in schizophrenia: Update on animal and clinical studies and strategies for the future.Neuropharmacology · 2020Review
- Training engagement, baseline cognitive functioning, and cognitive gains with computerized cognitive training: A cross-diagnostic study.Schizophrenia research. Cognition · 2020Article
- Individual Alpha Peak Frequency Moderates Transfer of Learning in Cognitive Remediation of Schizophrenia.Journal of the International Neuropsychological Society : JINS · 2020Article
- The Use of Cognitive Screening in Pharmacotherapy Trials for Cognitive Impairment Associated With Schizophrenia.Frontiers in psychiatry · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Cognitive remediation is aimed at reducing cognitive impairments in severe mental illnesses such as schizophrenia, but little is known about whether severity of cognitive impairment predicts benefit from this intervention. To address this question, this study aggregated data from five randomized controlled trials (N = 300) of a standardized comprehensive, multimodal outpatient cognitive remediation program, the Thinking Skills for Work program, and evaluated whether baseline level of cognitive impairment differentially predicted improvement in cognitive functioning following cognitive remediation vs. usual services. Using standardized scores of neuropsychological functioning to designate "low average," "moderate," and "severe" levels of cognitive impairment, participants with greater cognitive impairment were found to benefit differentially more from cognitive remediation than usual services compared to less cognitively impaired participants. The findings were unaffected by statistically controlling for participant demographic and clinical characteristics. The findings suggest that individuals with the greatest cognitive impairment, for whom cognitive remediation was developed, are also most likely to benefit from this intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.