Evidence map›Paper›PMID 30933669›Full record

ArticleJournal of hospital medicine2019

Association between Inpatient Delirium and Hospital Readmission in Patients ≥ 65 Years of Age: A Retrospective Cohort Study.

Sara C LaHue, Vanja C Douglas, Teresa Kuo, Carol A Conell, Vincent X Liu, S Andrew Josephson, Clay Angel, Kristen B Brooks

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of hospital medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07686900 (A Dynamic Early Warning System for Postoperative Delirium After Cardiac Surgery Integrating EEG, Cerebral Oxygenation, Hemodynamic Physiology, and Clinical Risk Factors), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07686900 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Dynamic Early Warning System for Postoperative Delirium After Cardiac Surgery Integrating EEG, Cerebral Oxygenation, Hemodynamic Physiology, and Clinical Risk Factors

Typeobservational_patient_registrySponsorSoutheast University, ChinaRan2026 to 2027Enrolled200ConditionsPostoperative Delirium, Cardiac Surgical Procedures
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Sara C LaHueDepartment of Neurology, School of Medicine, University of California, San Francisco, California.
Vanja C DouglasDepartment of Neurology, School of Medicine, University of California, San Francisco, California.
Teresa KuoDepartment of Medicine, Kaiser Permanente San Francisco Medical Center, San Francisco, California.
Carol A ConellDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Vincent X LiuDivision of Research, Kaiser Permanente Northern California, Oakland, California.
S Andrew JosephsonDepartment of Neurology, School of Medicine, University of California, San Francisco, California.
Clay AngelDepartment of Hospital Medicine, Kaiser Permanente San Rafael Medical Center, San Rafael, California.
Kristen B BrooksDepartment of Psychiatry, Kaiser Permanente San Rafael Medical Center, San Rafael, California.
University of California, San Francisco · USKaiser Permanente · USKaiser Permanente San Rafael Medical Center · USKaiser Permanente San Francisco Medical Center · US

Funding

Identifying pre-sepsis opportunities for early, targeted intervention - Equipment SupplementR35GM128672 · NIGMS · KAISER FOUNDATION RESEARCH INSTITUTE · PI Vincent Liu · 2018 to 2026
$4.3M
Data-driven Precision medicine in sepsisK23GM112018 · NIGMS · KAISER FOUNDATION RESEARCH INSTITUTE · PI LIU, VINCENT · 2014 to 2017
$768k
NIGMS NIH HHS K23 GM112018NIGMS NIH HHS R35 GM128672
6 · The paper itself

Abstract

backgroundDelirium affects more than seven million hospitalized adults in the United States annually. However, its impact on postdischarge healthcare utilization remains unclear.

objectiveTo determine the association between delirium and 30-day hospital readmission.

designA retrospective cohort study.

settingA general community medical and surgical hospital. PATIENTS: All adults who were at least 65 years old, without a history of delirium or alcohol-related delirium, and were hospitalized from September 2010 to March 2015. MEASUREMENTS: The patients deemed at risk for or displaying symptoms of delirium were screened by nurses using the Confusion Assessment Method with a followup by a staff psychiatrist for a subset of screen-positive patients. Patients with delirium confirmed by a staff psychiatrist were compared with those without delirium. The primary outcome was the 30-day readmission rate. The secondary outcomes included emergency department (ED) visits 30 days postdischarge, mortality during hospitalization and 30 days postdischarge, and discharge location.

resultsThe cohort included 718 delirious patients and 7,927 nondelirious patients. Using an unweighted multivariable logistic regression, delirium was determined to be significantly associated with the increased odds of readmission within 30 days of discharge (odds ratio (OR): 2.60; 95% CI, 1.96-3.44; P < .0001). Delirium was also significantly (P < .0001) associated with ED visits within 30 days postdischarge (OR: 2.18; 95% CI: 1.77-2.69) and discharge to a facility (OR: 2.52; 95% CI: 2.09-3.01).

conclusionsDelirium is a significant predictor of hospital readmission, ED visits, and discharge to a location other than home. Delirious patients should be targeted to reduce postdischarge healthcare utilization.

Indexed as

AgedBrief Psychiatric Rating ScaleCaliforniaDeliriumEmergency Service, HospitalFemaleHospitalizationHumansInpatientsMalePatient DischargePatient ReadmissionRetrospective Studies

Identifiers

PMID30933669
PMCPMC6628723
OpenAlexW2926148024

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.