ReviewThe Biological bulletin2019
GABA as a Neurotransmitter in Gastropod Molluscs.
Review in The Biological bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 45 citations in OpenAlex.
- Seasonal impact on the thermal tolerance window of a keystone coastal grazer, the common periwinkle Littorina littorea.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026Article
- Understanding Target-Specific Effects of Antidepressant Drug Pollution on Molluscs: A Systematic Review Report.Toxics · 2025Review
- Oxidative Stress-Mediated Neuroinflammation in the Pathophysiology of Schizophrenia.International journal of molecular sciences · 2025Review
- First evidence of an anxiety-like behavior and its pharmacological modulation in a molluscan model organism, Lymnaea stagnalis.Translational psychiatry · 2025Article
- Phagocytic Function Analyses of GABBiomedicines · 2025Article
- Insomnia treatment based on the regulation of the GABAergic system: traditional Chinese medicine perspectives and therapeutic approaches.Frontiers in neuroscience · 2025Review
- The effects of functional biscuits on intestinal mucosal microbiota composition, brain function, and antioxidant activity.Bioscience of microbiota, food and health · 2025Article
- Review
- An Enzyme Assay Kit for GABA Quantification in Plant Tissues.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Molecular characterization of nervous system organization in the hemichordate acorn worm Saccoglossus kowalevskii.PLoS biology · 2023Article
- α-Aminobutyric Acid Constrains Macrophage-Associated Inflammatory Diseases through Metabolic Reprogramming and Epigenetic Modification.International journal of molecular sciences · 2023Article
- GABRP is a Promising Prognostic Biomarker and Associated with Immune Cell Infiltration in Lung Squamous Cell Carcinoma.Pharmacogenomics and personalized medicine · 2023Article
- Understanding the function of the GABAergic system and its potential role in rheumatoid arthritis.Frontiers in immunology · 2023Review
- Histamine and gamma-aminobutyric acid in the nervous system of Pygospio elegans (Annelida: Spionidae): structure and recovery during reparative regeneration.BMC zoology · 2022Article
- Anxiolytic effect of YangshenDingzhi granules: Integrated network pharmacology and hippocampal metabolomics.Frontiers in pharmacology · 2022Article
- Freely chosen cadence during ergometer cycling is dependent on pedalling history.European journal of applied physiology · 2021Article
- United States Pharmacopeia (USP) Safety Review ofNutrients · 2021Review
- Identification and localization of a gonadotropin-releasing hormone-related neuropeptide in Biomphalaria, an intermediate host for schistosomiasis.The Journal of comparative neurology · 2021Article
- Genomic signatures of host-associated divergence and adaptation in a coral-eating snail,Ecology and evolution · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The neurotransmitter gamma-aminobutyric acid (GABA) is widely distributed in the mammalian central nervous system, where it acts as a major mediator of synaptic inhibition. GABA also serves as a neurotransmitter in a range of invertebrate phyla, including arthropods, echinoderms, annelids, nematodes, and platyhelminthes. This article reviews evidence supporting the neurotransmitter role of GABA in gastropod molluscs, with an emphasis on its presence in identified neurons and well-characterized neural circuits. The collective findings indicate that GABAergic signaling participates in the selection and specification of motor programs, as well as the bilateral coordination of motor circuits. While relatively few in number, GABAergic neurons can influence neural circuits via inhibitory, excitatory, and modulatory synaptic actions. GABA's colocalization with peptidergic and classical neurotransmitters can broaden its integrative capacity. The functional properties of GABAergic neurons in simpler gastropod systems may provide insight into the role of this neurotransmitter phenotype in more complex brains.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.