Evidence map›Paper›PMID 30933598›Full record

ArticleHealth affairs (Project Hope)2019

Measuring The Lifetime Costs Of Serious Mental Illness And The Mitigating Effects Of Educational Attainment.

Seth A Seabury, Sarah Axeen, Gwyn Pauley, Bryan Tysinger, Danielle Schlosser, John B Hernandez, Hanke Heun-Johnson, Henu Zhao, Dana P Goldman

Abstract read
In one paragraph

Article in Health affairs (Project Hope), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seth A SeaburySeth A. Seabury is an associate professor in the Department of Pharmaceutical and Health Economics at the School of Pharmacy and the Leonard D. Schaeffer Center for Health Policy and Economics, both at the University of Southern California (USC), in Los Angeles.
Sarah AxeenSarah Axeen ( axeen@usc.edu ) is an assistant professor of research at the Keck School of Medicine and the Schaeffer Center, both at USC.
Gwyn PauleyGwyn Pauley is a visiting assistant professor of economics at the University of Wisconsin-Madison.
Bryan TysingerBryan Tysinger is a research assistant professor at the Sol Price School of Public Policy and director of health policy microsimulation at the Schaeffer Center, both at USC.
Danielle SchlosserDanielle Schlosser is a senior clinical scientist at Verily Life Sciences LLC, in South San Francisco, California.
John B HernandezJohn B. Hernandez is a research scientist at Google Health, in Mountain View, California.
Hanke Heun-JohnsonHanke Heun-Johnson is a research associate at the Schaeffer Center, USC.
Henu ZhaoHenu Zhao is a senior quantitative analyst at the Schaeffer Center, USC.
Dana P GoldmanDana P. Goldman is the Leonard D. Schaeffer Chair and Distinguished Professor of Public Policy, Pharmacy, and Economics in the Sol Price School of Public Policy and School of Pharmacy, USC.

Funding

USC-Yale Roybal Center for Behavioral Interventions in AgingP30AG024968 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JASON N. DOCTOR · 2004 to 2026
$14.7M
USC Resource Center for Minority Aging Research (US-RCMAR)P30AG043073 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI EMMA AGUILA, JENNIFER A AILSHIRE · 2012 to 2026
$10.1M
NIA NIH HHS P30 AG024968NIA NIH HHS P30 AG043073
6 · The paper itself

Abstract

Serious mental illness (SMI) is a disabling condition that develops early in life and imposes substantial economic burden. There is a growing belief that early intervention for SMI has lifelong benefits for patients. However, assessing the cost-effectiveness of early intervention efforts is hampered by a lack of evidence on the long-term benefits. We addressed this by using a dynamic microsimulation model to estimate the lifetime burden of SMI for those diagnosed by age twenty-five. We estimated that the per patient lifetime burden of SMI is $1.85 million. We also found that a policy intervention focused on improving the educational attainment of people with SMI reduces the average per person burden of SMI by $73,600 (4.0 percent)-a change driven primarily by higher lifetime earnings-or over $8.9 billion in reduced burden per cohort of SMI patients. These findings provide a benchmark for the potential value of improving educational attainment for people with SMI.

Indexed as

Cost-Benefit AnalysisCost of IllnessAdolescentAdultAge FactorsChildChronic DiseaseDisability EvaluationEarly Intervention, EducationalFemaleHumansLife ExpectancyMaleMental DisordersMiddle AgedQuality-Adjusted Life Years

Identifiers

PMID30933598
PMCPMC6597007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.