Evidence map›Paper›PMID 30932696›Full record

ArticleAIDS patient care and STDs2019

Human Papillomavirus Vaccination and Infection in Young Sexual Minority Men: The P18 Cohort Study.

Perry N Halkitis, Pamela Valera, Caleb E LoSchiavo, Stephen E Goldstone, Maria Kanztanou, Anthony J Maiolatesi, Danielle C Ompad, Richard E Greene, Farzana Kapadia

Open access · greenAbstract read
In one paragraph

Article in AIDS patient care and STDs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Perry N Halkitis1 Departments of Biostatistics and Epidemiology and Urban-Global Health, School of Public Health, Rutgers University, Piscataway, New Jersey.
Pamela Valera1 Departments of Biostatistics and Epidemiology and Urban-Global Health, School of Public Health, Rutgers University, Piscataway, New Jersey.
Caleb E LoSchiavo1 Departments of Biostatistics and Epidemiology and Urban-Global Health, School of Public Health, Rutgers University, Piscataway, New Jersey.
Stephen E Goldstone6 Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
Maria Kanztanou7 Department of Epidemiology and Preventive Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Anthony J Maiolatesi2 Center for Health, Identity Behavior and Prevention Studies, Rutgers University, Newark, New Jersey.
Danielle C Ompad2 Center for Health, Identity Behavior and Prevention Studies, Rutgers University, Newark, New Jersey.
Richard E Greene2 Center for Health, Identity Behavior and Prevention Studies, Rutgers University, Newark, New Jersey.
Farzana Kapadia2 Center for Health, Identity Behavior and Prevention Studies, Rutgers University, Newark, New Jersey.
Rutgers, The State University of New Jersey · USEnvironmental and Occupational Health Sciences Institute · USIcahn School of Medicine at Mount Sinai · USNational and Kapodistrian University of Athens · GRNew York University · USNYU Langone Health · US

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan, Courtney McKnight · 1998 to 2026
$38.9M
Syndemic Production in Emergent Adult MenR01DA025537 · NIDA · RBHS-SCHOOL OF PUBLIC HEALTH · PI HALKITIS, PERRY N · 2009 to 2018
$6.0M
Application of a syndemic framework to HPV and HSV infection in emergent adult menR01AI132020 · NIAID · NEW YORK UNIVERSITY · PI HALKITIS, PERRY N, KAPADIA, FARZANA · 2017 to 2019
$2.3M
Application of a syndemic framework to HPV and HSV infection in emergent adult menR56AI122000 · NIAID · NEW YORK UNIVERSITY · PI HALKITIS, PERRY N, KAPADIA, FARZANA · 2015 to 2015
$584k
NIAID NIH HHS R01 AI132020NIAID NIH HHS R56 AI122000NIDA NIH HHS R01 DA025537
6 · The paper itself

Abstract

We examined the prevalence of infection with human papillomavirus (HPV) and HIV in a cohort of young gay, bisexual, and other men who have sex with men [sexual minority men (SMM)]. HPV vaccination uptake was assessed; HIV antibody testing was performed and genetic testing for oral and anal HPV infection was undertaken. We examined both HPV vaccination and infection in relation to key demographic and structural variables. Participants (n = 486) were on average 23 years old; 70% identified as a member of a racial/ethnic minority group, and 7% identified as transgender females. Only 18.1% of the participants indicated having received the full dosage of HPV vaccination and 45.1% were unvaccinated. Slightly over half the participants (58.6%) were infected with HPV, with 58.1% testing positive for anal infection and 8.8% for oral infection. HIV seropositivity was associated with infection to oral HPV [adjusted odds ratio (AOR) = 4.03] and vaccine-preventable HPV, whereas both neighborhood-level poverty (AOR = 1.68) and HIV infection (AOR = 31.13) were associated with anal infection to HPV (AOR = 1.68). Prevalence of HPV infection is high among unvaccinated young SMM, despite the availability and eligibility for vaccination. HPV infection adds further health burden to these populations and is particularly concerning for those who are HIV positive as HIV infection increases the risk of developing HPV-related cancers. These findings underscore a missed prevention opportunity for an at-risk and underserved population and suggest the need for active strategies to increase HPV vaccination uptake in young SMM before the onset of sexual behavior.

Indexed as

AdultAnal CanalBisexualityCohort StudiesEthnicityFemaleHIV InfectionsHomosexuality, MaleHumansMaleMinority GroupsPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesPrevalenceProspective StudiesPapillomavirus Vaccinescanceremerging adulthoodgay and bisexual menHIVHPVvaccination

Identifiers

PMID30932696
PMCPMC6459271
OpenAlexW2928279340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.