Evidence map›Paper›PMID 30932682›Full record

ArticlePhysical review letters2019

Direct Three-Dimensional Measurement of Refractive Index via Dual Photon-Phonon Scattering.

Antonio Fiore, Carlo Bevilacqua, Giuliano Scarcelli

Open access · greenAbstract read
In one paragraph

Article in Physical review letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Embedding two dimensional AlNature communications · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Brillouin microscopy.Nature reviews. Methods primers · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Optical elastography and tissue biomechanics.Journal of biomedical optics · 2019
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Antonio FioreFischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, USA.
Carlo BevilacquaFischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, USA.
Giuliano ScarcelliFischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, USA.
University of Maryland, College Park · US

Funding

Research Supplement - Quantitative analyses of tumor cell extravasationU01CA202177 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI KAMM, ROGER D · 2015 to 2020
$4.2M
Cornea biomechanical analysis with Brillouin microscopyR01EY028666 · NEI · UNIV OF MARYLAND, COLLEGE PARK · PI James Bradley Randleman, Giuliano Scarcelli · 2018 to 2026
$4.1M
Biomechanics of Neural Tube Development using Brillouin-OCT MultimodalityR01HD095520 · NICHD · UNIVERSITY OF HOUSTON · PI FINNELL, RICHARD H., LARIN, KIRILL V · 2018 to 2022
$3.3M
Brillouin confocal microscopy for biomechanical studies of metastatic cascade in 3D microenvironmentsR33CA204582 · NCI · UNIV OF MARYLAND, COLLEGE PARK · PI SCARCELLI, GIULIANO · 2016 to 2018
$849k
Development of 3D vascularized model of Blood Brain Barrier and its application to Alzheimer disease researchR21NS105027 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI KAMM, ROGER D · 2019 to 2020
$457k
NCI NIH HHS R33 CA204582NCI NIH HHS U01 CA202177NEI NIH HHS R01 EY028666NICHD NIH HHS R01 HD095520NINDS NIH HHS R21 NS105027
6 · The paper itself

Abstract

We developed a microscopy technique that can measure the local refractive index without sampling the optical phase delay of the electromagnetic radiation. To do this, we designed and experimentally demonstrated a setup with two colocalized Brillouin scattering interactions that couple to a common acoustic phonon axis; in this scenario, the ratio of Brillouin frequency shifts depends on the refractive index, but not on any other mechanical and/or optical properties of the sample. Integrating the spectral measurement within a confocal microscope, the refractive index is mapped at micron-scale three-dimensional resolution. As the refractive index is probed in epidetection and without assumptions on the geometrical dimensions of the sample, this method may prove useful to characterize biological cells and tissues.

Identifiers

PMID30932682
PMCPMC6530466
OpenAlexW2922266267

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.