Evidence map›Paper›PMID 30932376›Full record

ArticleJournal of Zhejiang University. Science. B

Mitochondrial superoxide anions induced by exogenous oxidative stress determine tumor cell fate: an individual cell-based study.

Hui Pan, Bao-Hui Wang, Zhou-Bin Li, Xing-Guo Gong, Yong Qin, Yan Jiang, Wei-Li Han

Open access · greenAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hui PanThe First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
Bao-Hui WangZhejiang Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou 310006, China.
Zhou-Bin LiThe First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
Xing-Guo GongInstitute of Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Yong QinInstitute of Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Yan JiangZhejiang Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou 310006, China.
Wei-Li HanThe First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
Zhejiang University · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveReactive oxygen species (ROS) are involved in a variety of biological phenomena and serve both deleterious and beneficial roles. ROS quantification and assessment of reaction networks are desirable but difficult because of their short half-life and high reactivity. Here, we describe a pro-oxidative model in a single human lung carcinoma SPC-A-1 cell that was created by application of extracellular H

methodsModified microfluidics and imaging techniques were used to determine O RESULTS AND

conclusionsResults from a modified microchip demonstrated that 1 mmol/L H

Indexed as

Oxidative StressApoptosisCalciumCalcium SignalingCaspasesCell LineageCell Line, TumorCytosolGlutathioneHumansHydrogen PeroxideMitochondriaOxidation-ReductionReactive Oxygen SpeciesSignal TransductionSuperoxidesCalciumCaspasesGlutathioneHydrogen PeroxideReactive Oxygen SpeciesSuperoxidesIndividual cell; Superoxide anion; Reactive oxygen species (ROS) dynamics; Intrinsic apoptotic pathway; Ca2+ signaling

Identifiers

PMID30932376
PMCPMC6454314
OpenAlexW2939551724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.