ArticleJournal of perinatology : official journal of the California Perinatal Association2019
Prenatal and postnatal inflammation-related risk factors for retinopathy of prematurity.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Gestational Age-Specific Prevalence of Retinopathy of Prematurity in Very Preterm Infants: An Exploratory Meta-Analysis.Acta paediatrica (Oslo, Norway : 1992) · 2026Pooled it
- Early-Onset Sepsis as an Early Predictor for Retinopathy of Prematurity: A Meta-analysis.American journal of perinatology · 2025Pooled it
- Histological Chorioamnionitis and Funisitis as New Risk Factors for Retinopathy of Prematurity: A Meta-analysis.American journal of perinatology · 2024Pooled it
- The relationship between inflammatory markers and retinopathy of prematurity in extremely premature infants.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Predictive value of serum inflammatory markers in retinopathy of prematurity.Eye (London, England) · 2024Article
- Predicting Retinopathy of Prematurity Risk Using Plasma Levels of Insulin-like Growth Factor 1 (IGF1), Tumor Necrosis Factor-Alpha (TNF-Alpha), and Neonatal Parameters.Clinics and practice · 2024Article
- Retinopathy of prematurity screening: prevalence and risk factors of ophthalmic complications in non-treated preterm infants.Eye (London, England) · 2024Article
- Neonatal sepsis as a cause of retinopathy of prematurity: An etiological explanation.Progress in retinal and eye research · 2024Review
- Dysregulation of histone deacetylases in ocular diseases.Archives of pharmacal research · 2024Review
- Risk factors for bronchopulmonary dysplasia infants with respiratory score greater than four: a multi-center, prospective, longitudinal cohort study in China.Scientific reports · 2023Article
- Complete blood count parameters as biomarkers of retinopathy of prematurity: a Portuguese multicenter study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- Cord blood transforming growth factor-β-induced as predictive biomarker of retinopathy of prematurity in preterm infants.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Association of Surgical Necrotizing Enterocolitis and Its Timing with Retinopathy of Prematurity.American journal of perinatology · 2023Article
- Association of inflammatory and angiogenic biomarkers in maternal plasma with retinopathy of prematurity in preterm infants.Eye (London, England) · 2023Article
- Identification of clinical factors associated with timing and duration of spontaneous regression of retinopathy of prematurity not requiring treatment.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Modifiable Risk Factors and Preventative Strategies for Severe Retinopathy of Prematurity.Life (Basel, Switzerland) · 2023Review
- Linked birth cohort files for perinatal health research: California as a model for methodology and implementation.Annals of epidemiology · 2023Article
- A Review on the Incidence and Related Risk Factors of Retinopathy of Prematurity Across Various Countries.Cureus · 2022Review
- Early and late onset sepsis and retinopathy of prematurity in a cohort of preterm infants.Scientific reports · 2022Article
- Retinopathy of prematurity: contribution of inflammatory and genetic factors.Molecular and cellular biochemistry · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate the relationship between prenatal and postnatal inflammation-related risk factors and severe retinopathy of prematurity (ROP). STUDY
designThe study included infants born <30 weeks in California from 2007 to 2011. Multivariable log-binomial regression was used to assess the association between prenatal and postnatal inflammation-related exposures and severe ROP, defined as stage 3-5 or surgery for ROP.
resultsOf 14,816 infants, 10.8% developed severe ROP. Though prenatal inflammation-related risk factors were initially associated with severe ROP, after accounting for the effect of these risk factors on gestational age at birth through mediation analysis, the association was non-significant (P = 0.6). Postnatal factors associated with severe ROP included prolonged oxygen exposure, sepsis, intraventricular hemorrhage, and necrotizing enterocolitis.
conclusionPostnatal inflammation-related factors were associated with severe ROP more strongly than prenatal factors. The association between prenatal inflammation-related factors and ROP was explained by earlier gestational age in infants exposed to prenatal inflammation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.