ArticleScientific reports2019
Altered neural activity to monetary reward/loss processing in episodic migraine.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Does losing money truly hurt? The shared neural bases of monetary loss and pain.Human brain mapping · 2022Pooled it
- Dopaminergic Dysregulation in Migraine: From Hypothalamic A11 Dysfunction to a Systemic Biobehavioral Phenotype.International journal of molecular sciences · 2026Review
- Mesocorticolimbic circuitry in episodic migraine: reward- and punishment-related responses and resting-state connectivity.The journal of headache and pain · 2026Article
- Acute neuroendocrine challenge elicits enhanced cortisol response and parallel transcriptomic changes in patients with migraine.Pain reports · 2025Article
- Dysfunctional mesocorticolimbic circuitry in cluster headache.The journal of headache and pain · 2025Article
- Pathophysiological changes in incentive processing in episodic migraine: a preliminary event-related potential study.Social cognitive and affective neuroscience · 2025Article
- A novel approach for migraine detection using localized component filtering and electroencephalographic spectral asymmetry index.Current journal of neurology · 2024Article
- Meditation Practice, Mindfulness, and Pain-Related Outcomes in Mindfulness-Based Treatment for Episodic Migraine.Mindfulness · 2023Article
- Circadian Variation of Migraine Attack Onset Affects fMRI Brain Response to Fearful Faces.Frontiers in human neuroscience · 2022Article
- Dopaminergic Regulation of Reward System Connectivity Underpins Pain and Emotional Suffering in Migraine.Journal of pain research · 2021Article
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11 authors.
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Abstract
The dysfunctions of the mesolimbic cortical reward circuit have been proposed to contribute to migraine pain. Although supporting empirical evidence was mainly found in connection with primary rewards or in chronic migraine where the pain experience is (almost) constant. Our goal however was to investigate the neural correlates of secondary reward/loss anticipation and consumption using the monetary incentive delay task in 29 episodic migraine patients and 41 headache-free controls. Migraine patients showed decreased activation in one cluster covering the right inferior frontal gyrus during reward consumption compared to controls. We also found significant negative correlation between the time of the last migraine attack before the scan and activation of the parahippocampal gyrus and the right hippocampus yielded to loss anticipation. During reward/loss consumption, a relative increase in the activity of the visual areas was observed the more time passed between the last attack and the scan session. Our results suggest intact reward/loss anticipation but altered reward consumption in migraine, indicating a decreased reactivity to monetary rewards. The findings also raise the possibility that neural responses to loss anticipation and reward/loss consumption could be altered by the proximity of the last migraine attack not just during pre-ictal periods, but interictally as well.
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