Evidence map›Paper›PMID 30931393›Full record

ArticleComputational psychiatry (Cambridge, Mass.)2019

Cost Evaluation During Decision-Making in Patients at Early Stages of Psychosis.

Anna O Ermakova, Nimrod Gileadi, Franziska Knolle, Azucena Justicia, Rachel Anderson, Paul C Fletcher, Michael Moutoussis, Graham K Murray

Open access · goldAbstract read
In one paragraph

Article in Computational psychiatry (Cambridge, Mass.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Active information sampling in health and disease.Neuroscience and biobehavioral reviews · 2025
    Review
  2. Boosting Serotonin Increases Information Gathering by Reducing Subjective Cognitive Costs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  3. Article
  4. Neural Circuitry of Salience and Reward Processing in Psychosis.Biological psychiatry global open science · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Anna O ErmakovaUnit for Social and Community Psychiatry, WHO Collaborating Centre for Mental Health Services Development, East London NHS Foundation Trust, London, UK.
Nimrod GileadiDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Franziska KnolleDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0002-9542-613X
Azucena JusticiaCambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK.
Rachel AndersonSchool of Clinical Medicine, University of Cambridge, Cambridge, UK.
Paul C FletcherDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Michael MoutoussisWellcome Centre for Human Neuroimaging and Max Planck Centre for Computational Psychiatry and Ageing, University College London, London, UK.ORCID https://orcid.org/0000-0002-4751-0425
Graham K MurrayDepartment of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0001-8296-1742
University of Cambridge · GBCambridgeshire and Peterborough NHS Foundation Trust · GBEast London NHS Foundation Trust · GBNeuroscience Institute · ITUniversity College London · GBWellcome/MRC Institute of Metabolic Science · GB

Funding

Medical Research Council G0001354Medical Research Council G0701911Medical Research Council G1000183Wellcome Trust 095692
6 · The paper itself

Abstract

Jumping to conclusions during probabilistic reasoning is a cognitive bias reliably observed in psychosis and linked to delusion formation. Although the reasons for this cognitive bias are unknown, one suggestion is that psychosis patients may view sampling information as more costly. However, previous computational modeling has provided evidence that patients with chronic schizophrenia jump to conclusions because of noisy decision-making. We developed a novel version of the classical beads task, systematically manipulating the cost of information gathering in four blocks. For 31 individuals with early symptoms of psychosis and 31 healthy volunteers, we examined the numbers of "draws to decision" when information sampling had no, a fixed, or an escalating cost. Computational modeling involved estimating a cost of information sampling parameter and a cognitive noise parameter. Overall, patients sampled less information than controls. However, group differences in numbers of draws became less prominent at higher cost trials, where less information was sampled. The attenuation of group difference was not due to floor effects, as in the most costly block, participants sampled more information than an ideal Bayesian agent. Computational modeling showed that, in the condition with no objective cost to information sampling, patients attributed higher costs to information sampling than controls did, Mann-Whitney

Indexed as

At Risk Mental Statebeadscognitive biascomputational psychiatryfishjumping to conclusionsschizophrenia

Identifiers

PMID30931393
PMCPMC6436576
OpenAlexW2952924172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.