ReviewBioMed research international2019
Benzoic Acid Used as Food and Feed Additives Can Regulate Gut Functions.
Review in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 112 citations in OpenAlex.
- Recombinant Echinococcus granulosus myophilin alleviates airway inflammation in mice with ovalbumin-induced allergic asthma via the gut microbiota-metabolite-immune axis.Parasites & vectors · 2026Article
- Analytical investigation of benzoic acid as a preservative agent in local and imported poultry products in Iraq.Open veterinary journal · 2026Article
- Benzoic acid decreases biological value of nitrogen without affecting nitrogen retention in nursery pigs fed crude protein-limited diets.Journal of animal science · 2026Article
- Mitigating antimicrobial resistance in the animal industry: reduction strategies and alternatives to antibiotics.Frontiers in veterinary science · 2026Review
- Effects of different acidifiers on the growth performance and diarrhea score of weaned piglets under commercial pig farm conditions.Translational animal science · 2026Article
- Effects of Low Benzoic Acid Concentrations on Growth and Substrate Utilization in Black Soldier Fly Larvae.Insects · 2025Article
- Application of dietary organic acids in laying hens production: a comprehensive review.Journal of animal science and technology · 2025Review
- Synergistic Enhancement of Humoral and Cellular Immunity in Attenuated Live Vaccines Using Chemical Nanoadjuvants: Evaluation of Sustained-Release Formulations.Veterinary sciences · 2025Article
- Benzoic acid-the cornerstone of any swine nutrition program.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Review
- Effect of Benzoic Acid on Nutrient Digestibility and Rectal Microbiota of Weaned Holstein Dairy Calves.Animals : an open access journal from MDPI · 2025Article
- Untargeted metabolomic profiling of serum and urine in kidney cancer: a non-invasive approach for biomarker discovery.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Metabolomics in Childhood Asthma - a Promising Tool to Meet Various Clinical Needs.Current allergy and asthma reports · 2025Review
- Synergistic Neuroprotective and Immunomodulatory Effects of Cocoa Seed Husk and Guarana Extract: A Nutraceutical Approach for Parkinson's Disease Management.Antioxidants (Basel, Switzerland) · 2025Article
- Alternatives to antibiotics for sustainable livestock production in the context of the One Health approach: tackling a common foe.Frontiers in veterinary science · 2025Review
- Multi-omics profiling reveals the role of 4-ethylbenzoic acid in promoting proliferation and invasion of cervical cancer.Frontiers in medicine · 2025Article
- Effects of benzoic acid in pig diets on nitrogen utilization, urinary pH, slurry pH, and odorous compounds.Animal bioscience · 2024Article
- Docosahexaenoic acid (DHA) alleviates inflammation and damage induced by experimental colitis.European journal of nutrition · 2024Article
- Therapeutic effects of oral benzoic acid application during acute murine campylobacteriosis.European journal of microbiology & immunology · 2024Article
- Metabolic Pathways Affected in Patients Undergoing Hemodialysis and Their Relationship with Inflammation.International journal of molecular sciences · 2024Article
- Protective Effect of Coated Benzoic Acid on Intestinal Epithelium in Weaned Pigs upon EnterotoxigenicAnimals : an open access journal from MDPI · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a kind of antibacterial and antifungal preservative, benzoic acid is widely used in foods and feeds. Recently, many studies showed that it could improve the growth and health, which should, at least partially, be derived from the promotion of gut functions, including digestion, absorption, and barrier. Based on the similarity of gut physiology between human and pigs, many relative studies in which piglets and porcine intestinal epithelial cells were used as the models have been done. And the results showed that using appropriate benzoic acid levels might improve gut functions via regulating enzyme activity, redox status, immunity, and microbiota, but excess administration would lead to the damage of gut health through redox status. However, the further mechanisms that some intestinal physiological functions might be regulated are not well understood. The present review will, in detail, summarize the effect of benzoic acid on gut functions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.