Evidence map›Paper›PMID 30931259›Full record

ArticleFrontiers in cellular and infection microbiology2019

Evaluation of the Magicplex™ Sepsis Real-Time Test for the Rapid Diagnosis of Bloodstream Infections in Adults.

Yuliya Zboromyrska, Catia Cillóniz, Nazaret Cobos-Trigueros, Manel Almela, Juan Carlos Hurtado, Andrea Vergara, Caterina Mata, Alex Soriano, Josep Mensa, Francesc Marco and 1 more

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

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  16. Molecular Methodologies for Improved Polymicrobial Sepsis Diagnosis.International journal of molecular sciences · 2022
    Review
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  18. Article
  19. Review
  20. A retrospective evaluation of a multiplex polymerase chain reaction test directly applied to blood for the management of sepsis in the critically ill.The Southern African journal of critical care : the official journal of the Critical Care Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yuliya ZboromyrskaThe Consortium of the Intercomarcal Laboratory of the Alt Penedès, Department of Microbiology, Vilafranca del Penedès, Spain.
Catia CillónizDepartment of Pneumology, Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Networked Biomedical Research Center for Respiratory Diseases (CIBERES), University of Barcelona, Barcelona, Spain.
Nazaret Cobos-TriguerosDepartment of Infectious Diseases, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Manel AlmelaThe Consortium of the Intercomarcal Laboratory of the Alt Penedès, Department of Microbiology, Vilafranca del Penedès, Spain.
Juan Carlos HurtadoDepartment of Microbiology, ISGlobal, Barcelona Centre for International Health Research, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Andrea VergaraDepartment of Microbiology, ISGlobal, Barcelona Centre for International Health Research, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Caterina MataSample Preparation Team, Centre Nacional d'Anàlisi Genòmica, Parc Científic de Barcelona - Torre I, Barcelona, Spain.
Alex SorianoDepartment of Infectious Diseases, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Josep MensaDepartment of Infectious Diseases, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Francesc MarcoDepartment of Microbiology, ISGlobal, Barcelona Centre for International Health Research, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Jordi VilaDepartment of Microbiology, ISGlobal, Barcelona Centre for International Health Research, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Universitat de Barcelona · ESBarcelona Institute for Global Health · ESCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESCentro Nacional de Análisis Genómico · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is a serious health condition worldwide, affecting more than 30 million people globally each year. Blood culture (BC) is generally used to diagnose sepsis because of the low quantity of microbes occurring in the blood during such infections. However, ~50% of bloodstream infections (BSI) give negative BC, this figure being higher for sepsis, which delays the start of appropriate antimicrobial therapy. This prospective study evaluated a multiplex real-time polymerase chain reaction, the Magicplex

Indexed as

BloodFemaleHumansMaleMiddle AgedMolecular Diagnostic TechniquesMultiplex Polymerase Chain ReactionProspective StudiesReal-Time Polymerase Chain ReactionSensitivity and SpecificitySepsisTime Factorsblood culturebloodstream infectioninfectionMagicplex™ Sepsis testPCR-based assaysepsis

Identifiers

PMID30931259
PMCPMC6423426
OpenAlexW2921162090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.