Evidence map›Paper›PMID 30931248›Full record

ArticleBiomedical spectroscopy and imaging2018

Observation of Angular Dependence of T1 in the Human White Matter at 3T.

Michael J Knight, Robin A Damion, Risto A Kauppinen

Open access · greenAbstract read
In one paragraph

Article in Biomedical spectroscopy and imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Field Strength-Dependent White Matter RMagnetic resonance in medicine · 2026
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  3. Fiber orientation-dependent TMagnetic resonance in medicine · 2025
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  12. The impact of head orientation with respect to BImaging neuroscience (Cambridge, Mass.) · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Static and dynamic BOLD fMRI components along white matter fibre tracts and their dependence on the orientation of the local diffusion tensor axis relative to the BJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  17. Article
  18. Measuring compartmental TNeuroImage · 2021
    Article
  19. Toward nonparametric diffusion-Magnetic resonance in medicine · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael J KnightSchool of Psychological Science, University of Bristol, Bristol, BS8 1TU, UK.
Robin A DamionSchool of Psychological Science, University of Bristol, Bristol, BS8 1TU, UK.
Risto A KauppinenSchool of Psychological Science, University of Bristol, Bristol, BS8 1TU, UK.
University of Bristol · GB

Funding

The Dunhill Medical Trust R385/1114Wellcome Trust
6 · The paper itself

Abstract

BACKGROUND AND

objectiveMultiple factors including chemical composition and microstructure influence relaxivity of tissue water

methodsAn inversion recovery (IR) pulse sequence with 6 inversion times for T1 and a multi-band diffusion tensor sequence with 60 diffusion sensitizing gradient directions for FA and the fibre-to-field angle θ (between the principal direction of diffusion and B

resultsOur data show that in the WM voxels with FA > 0.3 T1 becomes longer (i.e. 1/T1 = R1 slower) when fibre-to-field angle is 50-60°, approximating the magic angle of 54.7°. The longer T1 around the magic angle was found in a number of WM tracts independent of anatomy. S0 signal intensity, computed from IR fits, mirrored that of T1 being greater in the WM voxels when the fibre-to-field angle was 50-60°.

conclusionsThe current data point to fibre-to-field-angle dependent T1 relaxation in WM as an indication of effects of microstructure on the longitudinal relaxation of water.

Indexed as

Longitudinal relaxation timerelaxation anisotropywhite matter

Identifiers

PMID30931248
PMCPMC6436728
OpenAlexW2889654156

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.