Evidence map›Paper›PMID 30931112›Full record

ArticleMolecular and clinical oncology2019

Management of primary squamous cell carcinoma of the pancreas with a nanosomal paclitaxel lipid suspension-based regimen: A case report.

Saroj Kumar Das Majumdar, Dillip Kumar Muduly, Subhasis Mishra, Chinmaya Rashmi Ranjan Mohapatra, Deepak Bunger, Mujtaba A Khan

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Treatment with nanosomal paclitaxel lipid suspensionTherapeutic advances in medical oncology · 2024
    Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Saroj Kumar Das MajumdarDepartment of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India.
Dillip Kumar MudulyDepartment of Surgical Oncology, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India.
Subhasis MishraDepartment of Surgical Oncology, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India.
Chinmaya Rashmi Ranjan MohapatraDepartment of Surgical Oncology, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India.
Deepak BungerDepartment of Medical Affairs and Clinical Development, Intas Pharmaceuticals Ltd., Ahmedabad, Gujarat 380054, India.
Mujtaba A KhanDepartment of Medical Affairs and Clinical Development, Intas Pharmaceuticals Ltd., Ahmedabad, Gujarat 380054, India.
All India Institute of Medical Sciences Bhubaneswar · INIntas Pharmaceuticals (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Squamous cell carcinoma (SCC) of the pancreas is a rare tumor with only a few case reports available. It is an aggressive form of pancreatic cancer with a poor prognosis. The diagnosis and optimal management of SCC of the pancreas is poorly defined due to the lack of standard treatment or guidelines and owing to the rarity of this malignancy. Patients suffering from SCC of the pancreas do not respond well to chemotherapy or radiotherapy and isolated reports are available on the use of gemcitabine and newer taxane formulations. Surgical resection of the tumor is the most effective modality; however, due to a delay in diagnosis, the majority of pancreatic SCCs remain unresectable. Herein, a case of SCC of the pancreatic tail is reported in a 60-year-old patient who was managed with a combination of albumin-free nanosomal paclitaxel lipid suspension (NPLS) and gemcitabine in a neoadjuvant setting. To the best of our knowledge, this is the first such case report of a locally advanced SCC of the pancreatic tail showing an overall survival of 1 year following treatment with an NPLS based regimen. The treatment was well tolerated with no serious safety concerns.

Indexed as

nanosomal paclitaxel lipid suspensionPacliAqualippancreatic cancerpancreatic tailsquamous cell carcinoma

Identifiers

PMID30931112
PMCPMC6425502
OpenAlexW2916026110

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.