Evidence map›Paper›PMID 30931108›Full record

ArticleRSC advances2019

A convenient workflow to spot photosensitizers revealed photo-activity in basidiomycetes.

Bianka Siewert, Pamela Vrabl, Fabian Hammerle, Isabella Bingger, Hermann Stuppner

Abstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
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  4. Optimized isolation of 7,7'-biphyscion starting from Cortinarius rubrophyllus, a chemically unexplored fungal species rich in photosensitizers.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Does the chemistry of fungal pigments demand the existence of photoactivated defense strategies in basidiomycetes?Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bianka SiewertInstitute of Pharmacy/Pharmacognosy, Center for Molecular Biosciences Innsbruck (CMBI), Center for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, Innsbruck, 6020 Austria. Email: Bianka.siewert@uibk.ac.at.ORCID 0000-0002-4910-1756
Pamela VrablInstitute of Microbiology, University of Innsbruck, Technikerstraße 25d, Innsbruck, 6020 Austria.ORCID 0000-0002-8104-8684
Fabian HammerleInstitute of Pharmacy/Pharmacognosy, Center for Molecular Biosciences Innsbruck (CMBI), Center for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, Innsbruck, 6020 Austria. Email: Bianka.siewert@uibk.ac.at.
Isabella BinggerInstitute of Microbiology, University of Innsbruck, Technikerstraße 25d, Innsbruck, 6020 Austria.
Hermann StuppnerInstitute of Pharmacy/Pharmacognosy, Center for Molecular Biosciences Innsbruck (CMBI), Center for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, Innsbruck, 6020 Austria. Email: Bianka.siewert@uibk.ac.at.ORCID 0000-0001-8862-0201

Funding

Austrian Science Fund FWF T 862
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is an alternative approach for the treatment of neoplastic diseases employing photosensitizers activated by light. In order to discover new natural photosensitizers, a convenient workflow was established. To validate the workflow, fungi were selected, because we hypothesized that fruiting bodies and mycelia are an overlooked source. The results proved the hypothesis, as exorbitant high photo-cytotoxicity values were detected. For example, the acetone extract of

Identifiers

PMID30931108
PMCPMC6394893

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.