Evidence map›Paper›PMID 30931101›Full record

ArticleToxicology research2019

Effects of long-term exposure to aluminum in the hippocampus in the type 2 diabetes model rats.

Sung Min Nam, Dae Young Yoo, Hyun Jung Kwon, Jong Whi Kim, Hyo Young Jung, Dae Won Kim, Je Kyung Seong, In Koo Hwang, Yeo Sung Yoon

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Sung Min NamDepartment of Anatomy and Cell Biology , College of Veterinary Medicine , and Research Institute for Veterinary Science , Seoul National University , Seoul 08826 , South Korea . Email: ysyoon@snu.ac.kr ; ; Tel: +82 2 8801264.
Dae Young YooDepartment of Anatomy and Cell Biology , College of Veterinary Medicine , and Research Institute for Veterinary Science , Seoul National University , Seoul 08826 , South Korea . Email: ysyoon@snu.ac.kr ; ; Tel: +82 2 8801264.
Hyun Jung KwonDepartment of Biochemistry and Molecular Biology , Research Institute of Oral Sciences , College of Dentistry , Gangneung-Wonju National University , Gangneung 25457 , South Korea.
Jong Whi KimDepartment of Anatomy and Cell Biology , College of Veterinary Medicine , and Research Institute for Veterinary Science , Seoul National University , Seoul 08826 , South Korea . Email: ysyoon@snu.ac.kr ; ; Tel: +82 2 8801264.
Hyo Young JungDepartment of Anatomy and Cell Biology , College of Veterinary Medicine , and Research Institute for Veterinary Science , Seoul National University , Seoul 08826 , South Korea . Email: ysyoon@snu.ac.kr ; ; Tel: +82 2 8801264.
Dae Won KimDepartment of Biochemistry and Molecular Biology , Research Institute of Oral Sciences , College of Dentistry , Gangneung-Wonju National University , Gangneung 25457 , South Korea.
Je Kyung SeongDepartment of Anatomy and Cell Biology , College of Veterinary Medicine , and Research Institute for Veterinary Science , Seoul National University , Seoul 08826 , South Korea . Email: ysyoon@snu.ac.kr ; ; Tel: +82 2 8801264.
In Koo HwangDepartment of Anatomy and Cell Biology , College of Veterinary Medicine , and Research Institute for Veterinary Science , Seoul National University , Seoul 08826 , South Korea . Email: ysyoon@snu.ac.kr ; ; Tel: +82 2 8801264.ORCID 0000-0002-0533-4638
Yeo Sung YoonDepartment of Anatomy and Cell Biology , College of Veterinary Medicine , and Research Institute for Veterinary Science , Seoul National University , Seoul 08826 , South Korea . Email: ysyoon@snu.ac.kr ; ; Tel: +82 2 8801264.ORCID 0000-0002-6711-0744
Seoul National University · KRGangneung–Wonju National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the long-term effects of aluminum (Al) exposure in the hippocampus in Zucker diabetic fatty (ZDF) rats and Zucker lean control (ZLC) rats. Six-week-old ZLC and ZDF rats were randomly divided into Al- and non-Al-groups. They were sacrificed 27 weeks after Al exposure (2000 ppm) through drinking water. Al exposure did not affect physiological parameters such as the body weight and blood glucose levels, but the prolonged diabetic condition had significant effects on the body weight and blood glucose levels. To determine the effects of diabetes and Al exposure on the neural plasticity and inflammatory response in the hippocampus, we examined the levels of doublecortin (DCX),

Identifiers

PMID30931101
PMCPMC6404161
OpenAlexW2903539693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.