Evidence map›Paper›PMID 30931099›Full record

ArticleToxicology research2019

Fresh and ozonized black carbon promoted DNA damage and repair responses in A549 cells.

Jing An, Huixin He, Lu Wang, Yingying Jin, Jiexing Kong, Yufang Zhong, Mingyuan Liu, Yu Shang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jing AnSchool of Environmental and Chemical Engineering , Shanghai University , Shanghai 200444 , China . Email: yushang@shu.edu.cn ; Tel: +86 21 66137736.ORCID 0000-0003-0885-8979
Huixin HeSchool of Environmental and Chemical Engineering , Shanghai University , Shanghai 200444 , China . Email: yushang@shu.edu.cn ; Tel: +86 21 66137736.
Lu WangSchool of Environmental and Chemical Engineering , Shanghai University , Shanghai 200444 , China . Email: yushang@shu.edu.cn ; Tel: +86 21 66137736.ORCID 0000-0002-4510-8723
Yingying JinSchool of Environmental and Chemical Engineering , Shanghai University , Shanghai 200444 , China . Email: yushang@shu.edu.cn ; Tel: +86 21 66137736.
Jiexing KongSchool of Environmental and Chemical Engineering , Shanghai University , Shanghai 200444 , China . Email: yushang@shu.edu.cn ; Tel: +86 21 66137736.
Yufang ZhongSchool of Environmental and Chemical Engineering , Shanghai University , Shanghai 200444 , China . Email: yushang@shu.edu.cn ; Tel: +86 21 66137736.
Mingyuan LiuDepartment of Neurology , Yueyang Hospital of Integrated Chinese and Western Medicine , Shanghai University of Traditional Chinese Medicine , Shanghai 200437 , China . Email: Liu.mingyuan@foxmail.com ; Tel: +86 21 65161782.
Yu ShangSchool of Environmental and Chemical Engineering , Shanghai University , Shanghai 200444 , China . Email: yushang@shu.edu.cn ; Tel: +86 21 66137736.ORCID 0000-0001-8030-9347
Shanghai University · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nano-sized ambient black carbon (BC) is hypothesized to pose a serious threat to human health. After emission into the air, the atmospheric oxidation process can modify its physiochemical properties and change its biological responses. In this study, we aimed to compare different DNA damage and repair responses promoted by fresh BC (FBC) and ozone oxidized-BC (OBC). The cell apoptosis, cell arrest, DNA damage and repair were investigated in A549 cells after treatment with FBC and OBC. Associated gene expressions were measured with the reverse transcription quantitative polymerase chain reaction (RT-qPCR) method. Both FBC and OBC could induce cell apoptosis in A549 cells with up-regulated gene of promyelocytic leukemia protein (

Identifiers

PMID30931099
PMCPMC6404160
OpenAlexW2902296651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.