ArticleHong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao2017
Combined transcranial and trans-spinal direct current stimulation in chronic headache: A feasibility and safety trial for a novel intervention.
Article in Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07055373 (The Safety and Feasibility of Transauricular Vagus Nerve Stimulation Therapy in Chronic Whiplash-Associated Disorders), which is not on this map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Safety and Feasibility of Transauricular Vagus Nerve Stimulation Therapy in Chronic Whiplash-Associated Disorders: A Randomized Pilot Trial
Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Trial
- Hallmarks of primary headache: part 2- Tension-type headache.The journal of headache and pain · 2025Review
- Neuromodulation in Chronic Migraine: Evidence and Recommendations from the GRADE Framework.Advances in therapy · 2025Review
- [Using electricity to combat headache : Electrotherapy and tDCS in the 1870s/1880s and today].Schmerz (Berlin, Germany) · 2025Review
- Interventional neuromodulation techniques for cervicogenic headache.Journal of anesthesia and translational medicine · 2025Article
- The safety and feasibility of transcranial direct current stimulation combined with conservative treatment for patients with cervicogenic headaches: A double-blinded randomized control study protocol.Contemporary clinical trials communications · 2024Article
- Modeling Electric Fields in Transcutaneous Spinal Direct Current Stimulation: A Clinical Perspective.Biomedicines · 2023Review
- Time since onset might be of essence: A recommendation to assess the effects of combination of non-pharmacological neuromodulatory approaches at early stage since symptoms onset.Frontiers in neurology · 2023Article
- Update of Neuromodulation in Chronic Migraine.Current pain and headache reports · 2021Review
- Transcranial Direct Current Stimulation and Migraine-The Beginning of a Long Journey.Journal of clinical medicine · 2020Article
- Assessing adverse effects and unspecific effects of transcutaneous spinal direct current stimulation (tsDCS).Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic primary headache disorders are associated with frequent, severe pain and significant functional impairment, with treatment remaining challenging.
objectiveWe examined the feasibility and safety of a novel brain [transcranial direct current stimulation (tDCS)] and spinal cord stimulation [trans-spinal cord direct current stimulation (tsDCS)] treatment in chronic headache.
methodsNine participants (3 males; aged, 40 ± 15 years) suffering from chronic daily headache, chronic tension-type headache, or chronic migraine received the combined brain and spinal cord intervention for 5 consecutive days. Stimulation was applied for a total of 40 minutes (20 minutes of tDCS followed by 20 minutes of tsDCS) at 1 mA. Pain sensitivity and headache symptoms (frequency, severity, duration, and medications recorded via a headache diary, 4 weeks before and after treatment) were assessed.
resultsThe treatment was safe, feasible, and well tolerated. Headache frequency was reduced following the treatment (
conclusionThese data suggest that combined tDCS and tsDCS intervention is safe and feasible, and may improve headache frequency in patients with chronic primary headache disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.