Evidence map›Paper›PMID 30930962›Full record

ArticleMolecular cytogenetics2019

Cell maps on the human genome.

Christopher Cherniak, Raul Rodriguez-Esteban

Abstract read
In one paragraph

Article in Molecular cytogenetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christopher CherniakCommittee for Philosophy and the Sciences, Department of Philosophy, University of Maryland, College Park, MD 20742 USA.ORCID 0000-0002-5244-096X
Raul Rodriguez-EstebanCommittee for Philosophy and the Sciences, Department of Philosophy, University of Maryland, College Park, MD 20742 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe have previously described evidence for a statistically significant, global, supra-chromosomal representation of the human body that appears to stretch over the entire genome.

resultsHere, we extend the genome mapping model, zooming down to the typical individual animal cell. Its cellular organization appears to be significantly mapped onto the human genome: Evidence is reported for a "cellunculus" - on the model of a homunculus, on the

conclusionsBasic cell structure turns out to map similarly onto the total genome, mirrored via genes that express in particular cell organelles (e.g., "nuclear membrane"). Similar cell maps may also appear on individual chromosomes that map topologically on the dorsoventral body axis. This seems to constitute some of the basic structural and functional organization of nucleus and chromosome architecture.

Indexed as

“Cellunculus”Connection optimizationGenomeHomunculusOrganelle-specific geneSomatotopic map

Identifiers

PMID30930962
PMCPMC6425595

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.