Evidence map›Paper›PMID 30930959›Full record

ArticleResearch in autism spectrum disorders2018

Interaction between manganese and

Mohammad H Rahbar, Maureen Samms-Vaughan, MinJae Lee, MacKinsey A Christian, Jan Bressler, Manouchehr Hessabi, Megan L Grove, Sydonnie Shakespeare-Pellington, Charlene Coore Desai, Jody-Ann Reece and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Research in autism spectrum disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
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  7. Article
  8. Article
  9. Associations of Metabolic Genes (International journal of environmental research and public health · 2021
    Article
  10. Correlation between concentrations of four heavy metals in cord blood and childhood blood of Jamaican children.Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering · 2021
    Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Mohammad H RahbarDepartment of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
Maureen Samms-VaughanDepartment of Child & Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
MinJae LeeDivision of Clinical and Translational Sciences, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
MacKinsey A ChristianDepartment of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
Jan BresslerDepartment of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
Manouchehr HessabiBiostatistics/Epidemiology/Research Design (BERD) core, Center for Clinical and Translational Sciences (CCTS), The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
Megan L GroveDepartment of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
Sydonnie Shakespeare-PellingtonDepartment of Child & Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
Charlene Coore DesaiDepartment of Child & Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
Jody-Ann ReeceDepartment of Child & Adolescent Health, The University of the West Indies (UWI), Mona Campus, Kingston, Jamaica.
Katherine A LovelandDepartment of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77054, USA.
Compton BeecherDepartment of Basic Medical Sciences, The University of the West Indies, Mona Campus, Kingston, Jamaica.
Wayne McLaughlinDepartment of Basic Medical Sciences, The University of the West Indies, Mona Campus, Kingston, Jamaica.
Eric BoerwinkleDepartment of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
The University of Texas Health Science Center at Houston · USUniversity of the West Indies · JMUniversity of the West Indies System · JM

Funding

Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
Epidemiological Research on Autism in Jamaica - Phase IIR01ES022165 · NIEHS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RAHBAR, MOHAMMAD HOSSEIN · 2013 to 2018
$2.8M
Epidemiological Research on Autism in JamaicaR21HD057808 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RAHBAR, MOHAMMAD HOSSEIN · 2009 to 2010
$278k
NCATS NIH HHS UL1 TR000371NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR003167NCRR NIH HHS UL1 RR024148NICHD NIH HHS R21 HD057808NIEHS NIH HHS R01 ES022165
6 · The paper itself

Abstract

backgroundWe previously reported a significant interactive association between polymorphisms of

methodWe used data from 163 case-control pairs of children 2-8 years of age from our autism project in Jamaica, in which we collected blood for heavy metals analysis at enrollment. To minimize potential multicollinearity between concentrations of the four metals, we generated a mixture index using generalized weighted quantile sum regression, which was used in conditional logistic regression models to control for the four metals while assessing the interactive association between

resultsSimilar to the findings we reported previously, we found that in co-dominant and dominant models for

conclusionsAfter adjusting for the mixture of four metals, the interactive association of BMC and

Indexed as

Autism spectrum disorder (ASD)GSTPPHeavy metalsInteractionWeighted quantile sum (WQS) regression

Identifiers

PMID30930959
PMCPMC6434704
OpenAlexW2892282274

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.