Evidence map›Paper›PMID 30930900›Full record

ArticleFrontiers in immunology2019

Combined IL-2 Immunocomplex and Anti-IL-5 mAb Treatment Expands Foxp3

Hirohito Abo, Kyle L Flannigan, Duke Geem, Vu L Ngo, Akihito Harusato, Timothy L Denning

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. [Advanced Combination Therapy in Inflammatory Bowel Disease].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hirohito AboCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia.
Kyle L FlanniganCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia.
Duke GeemCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia.
Vu L NgoCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia.
Akihito HarusatoCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia.
Timothy L DenningCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia.
Georgia State University · US

Funding

Intestinal Antigen Presenting Cells and Mucosal ImmunityR01DK097256 · NIDDK · GEORGIA STATE UNIVERSITY · PI DENNING, TIMOTHY L · 2013 to 2017
$1.6M
Novel Therapeutic Approaches For Treatment of Intestinal InflammationR01DK107739 · NIDDK · GEORGIA STATE UNIVERSITY · PI DENNING, TIMOTHY L, MERLIN, DIDIER · 2017 to 2020
$1.4M
BLRD VA IK6 BX004476NIDDK NIH HHS R01 DK097256NIDDK NIH HHS R01 DK107739
6 · The paper itself

Abstract

Interleukin (IL)-2 is expressed during T cell activation and induces the proliferation and differentiation of T cells. CD4

Indexed as

AnimalsAntibodies, MonoclonalColitisDextran SulfateDisease Models, AnimalEosinophiliaInterleukin-2Interleukin-5MiceT-Lymphocytes, RegulatoryAntibodies, MonoclonalDextran SulfateInterleukin-2Interleukin-5eosinophilIBDIL-2IL-5ILC2Treg

Identifiers

PMID30930900
PMCPMC6428029
OpenAlexW2916575199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.