Trial reportFrontiers in immunology2019
Differential Patterns of IgG Subclass Responses to
Open access · goldAbstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
In one paragraph
Trial report in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 86 citations in OpenAlex.
- R21/Matrix-M malaria vaccine drives diverse immune responses in pre-exposed adults: insights from a phase IIb controlled human malaria infection trial.Frontiers in immunology · 2025Trial
- Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children.Malaria journal · 2023Trial
- Antibody Responses to the ConservedPathogens (Basel, Switzerland) · 2026Article
- Antibody-Dependent Neutrophil Phagocytosis of Plasmodium falciparum-Infected Erythrocytes Is Mediated by FcγRIIa.The Journal of infectious diseases · 2026Article
- Malaria-diabetes comorbidity is linked to higher parasitaemia and enhanced IgG response to malaria vaccine candidate antigens.PloS one · 2026Article
- mRNA delivery of circumsporozoite protein epitope-based malaria vaccines induces protection in a mouse model.NPJ vaccines · 2025Article
- Immunoinformatics-Based Multi-Epitope Vaccine Design AgainstHealth science reports · 2025Article
- Role of malaria exposure and off-target responses on RTS,S/AS02NPJ vaccines · 2025Article
- Leveraging the Polymorphism of the Merozoite Surface Protein 2 (MSP2) to Engineer Molecular Tools for Predicting Malaria Episodes in a Community.International journal of molecular sciences · 2025Article
- Correlation of Inflammatory Biomarkers and IgG4 Antibodies with Malaria in Cameroon's Buea Municipality Children.Diseases (Basel, Switzerland) · 2025Article
- Functionality of Toxoplasma gondii antibodies in a population of Beninese pregnant women exposed to malaria.Scientific reports · 2025Article
- B-cell epitope mapping and characterization of antibody responses to recombinant PvRipr in malaria-exposed individuals.Frontiers in immunology · 2025Article
- Association of the humoral immune response with the inflammatory profile in Plasmodium vivax infections in pregnant women.PLoS neglected tropical diseases · 2024Observational
- Article
- Dynamics of IgM and IgG Antibody Response Profile against Linear B-Cell Epitopes from Exoerythrocytic (CelTOS and TRAP) and Erythrocytic (CyRPA) Phases ofAntibodies (Basel, Switzerland) · 2024Article
- Mature beyond their years: young children who escape detection of parasitemia despite living in settings of intense malaria transmission.Biochemical Society transactions · 2024Review
- IgG and IgM responses to the Plasmodium falciparum asexual stage antigens reflect respectively protection against malaria during pregnancy and infanthood.Malaria journal · 2024Article
- Article
- Antibody-Dependent Respiratory Burst againstVaccines · 2024Article
- Non-neutralizing functions in anti-SARS-CoV-2 IgG antibodies.Biomedical journal · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 13 institutions in 8 countries.
Carlota DobañoISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Rebeca SantanoISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Marta VidalISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Alfons JiménezISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Chenjerai JairoceCentro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique.
Itziar UbillosISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
David DosooKintampo Health Research Centre, Kintampo, Ghana.
Ruth AguilarISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Nana Aba WilliamsISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Núria Díez-PadrisaISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Aintzane AyestaranISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Clarissa ValimDepartment of Osteopathic Medical Specialties, Michigan State University, East Lansing, MI, United States.
Kwaku Poku AsanteKintampo Health Research Centre, Kintampo, Ghana.
Seth Owusu-AgyeiKintampo Health Research Centre, Kintampo, Ghana.
David LanarMalaria Vaccine Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States.
Virander ChauhanMalaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.
Chetan ChitnisMalaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.
Sheetij DuttaMalaria Vaccine Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States.
Evelina AngovMalaria Vaccine Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States.
Benoit GamainUnité Biologie Intégrée du Globule Rouge, Laboratoire d'Excellence GR-Ex, UMR_S1134, Inserm, INTS, Université Sorbonne Paris Cité, Université Paris Diderot, Paris, France.
Ross L CoppelInfection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Melbourne, VIC, Australia.
James G BeesonBurnet Institute, Melbourne, VIC, Australia.
Linda ReilingBurnet Institute, Melbourne, VIC, Australia.
Deepak GaurMalaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.
David CavanaghAshworth Laboratories, Centre for Immunity, Infection and Evolution, School of Biological Sciences, Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, United Kingdom.
Ben GyanKintampo Health Research Centre, Kintampo, Ghana.
Augusto J NhabombaCentro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique.
Joseph J CampoISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Gemma MoncunillISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Universitat de Barcelona · ESBarcelona Institute for Global Health · ESKintampo Health Research Centre · GHWalter Reed Army Institute of Research · USBurnet Institute · AUInternational Centre for Genetic Engineering and Biotechnology · INManhiça Health Research Centre · MZAustralian Regenerative Medicine Institute · AUCentre for Immunity, Infection and Evolution · GBJawaharlal Nehru University · INLondon School of Hygiene & Tropical Medicine · GBMichigan State University · USSorbonne Paris Cité · FR
Funding
Understanding RTS,S malaria vaccine-induced protection through integrated analysiR01AI095789 · NIAID · BARCELONA INTERNATIONAL HEALTH RES CTR · PI DOBANO, CARLOTA · 2012 to 2016
$3.2MNIAID NIH HHS R01 AI095789
Abstract
Naturally acquired immunity (NAI) to
Indexed as
Adaptive ImmunityAntigens, ProtozoanFemaleHumansImmunoglobulin GInfantMalariaMalaria VaccinesMalePlasmodium falciparumVaccinationAntigens, ProtozoanImmunoglobulin GMalaria VaccinesantibodychildrenIgG subclassMalarianaturally acquired immunityPlasmodium falciparumprotectionvaccine
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.