Evidence map›Paper›PMID 30930628›Full record

ArticleTurkish journal of biology = Turk biyoloji dergisi2018

Oxidative Stress Upregulates the Transcription of Genes Involved in Thiamine Metabolism.

Burcu Kartal, Ahmet Akçay, Bedia Palabiyik

Open access · bronzeAbstract read
In one paragraph

Article in Turkish journal of biology = Turk biyoloji dergisi, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  5. Adaptive laboratory evolution ofFrontiers in microbiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Burcu KartalDepartment of Genetics and Bioengineering, Faculty of Engineering, Alanya Alaaddin Keykubat University , Antalya , Turkey.ORCID https://orcid.org/0000-0003-2354-7212
Ahmet AkçayDepartment of Molecular Biology and Genetics, Institute of Graduate Studies in Science and Engineering, İstanbul University , İstanbul , Turkey.ORCID https://orcid.org/0000-0002-9836-4165
Bedia PalabiyikDepartment of Molecular Biology and Genetics, Faculty of Science, İstanbul University , İstanbul , Turkey.ORCID https://orcid.org/0000-0002-3395-3081
Istanbul University · TRAlanya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiamine is a major vitamin that acts as a cofactor in energy metabolism in all organisms, as well as in lipid and amino acid metabolisms, and is associated with many diseases. It is known that glucose starvation decreases the intracellular thiamine pool while increasing oxidative stress tolerance. Earlier, in whole genome analysis, we detected major differences in the expression of genes related to thiamine pathway against oxidative stress in Schizosaccharomyces pombe. We investigated the effects of oxidative stress and glucose repression to thiamine pathway in S. pombe by comparing some genes encoding key enzymes of each related pathway at the transcription level. In the present study, we found that the expression of genes related to thiamine biosynthesis and transport (thi2, thi3, and pho1) increased in wild type and ird11 cells grown in thiamine-rich media under oxidative stress induced by H2O2. Based on our findings, we suggested that there might be an important effect of oxidative stress on thiamine biosynthesis and transport.

Indexed as

Fission yeastglucose metabolismoxidative stressthiamine

Identifiers

PMID30930628
PMCPMC6438119
OpenAlexW2898502055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.