Evidence map›Paper›PMID 30930550›Full record

ArticleSynlett : accounts and rapid communications in synthetic organic chemistry2019

Engineered Cytochrome

Kai Chen, Xiongyi Huang, Shuo-Qing Zhang, Andrew Z Zhou, S B Jennifer Kan, Xin Hong, Frances H Arnold

Open access · hybridAbstract read
In one paragraph

Article in Synlett : accounts and rapid communications in synthetic organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. bioRxiv : the preprint server for biology · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Origin and Control of Chemoselectivity in CytochromeJournal of the American Chemical Society · 2021
    Article
  7. Review
  8. Article
  9. Unlocking the therapeutic potential of artificial metalloenzymes.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2020
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kai ChenDivision of Chemistry and Chemical Engineering 210-41, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-3325-3536
Xiongyi HuangDivision of Chemistry and Chemical Engineering 210-41, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0001-7156-8881
Shuo-Qing ZhangDepartment of Chemistry, Zhejiang University, Hangzhou, Zhejiang 31007, P. R. of China.ORCID 0000-0002-7617-3042
Andrew Z ZhouDivision of Chemistry and Chemical Engineering 210-41, California Institute of Technology, Pasadena, CA 91125, USA.
S B Jennifer KanDivision of Chemistry and Chemical Engineering 210-41, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0001-6371-8042
Xin HongDepartment of Chemistry, Zhejiang University, Hangzhou, Zhejiang 31007, P. R. of China.ORCID 0000-0003-4717-2814
Frances H ArnoldDivision of Chemistry and Chemical Engineering 210-41, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-4027-364X
Division of Chemistry · US

Funding

Expanding the chemistry of life: New enzymatic platforms for synthesis of bioactive organofluorinesK99GM129419 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HUANG, XIONGYI · 2018 to 2019
$95k
NIGMS NIH HHS K99 GM129419
6 · The paper itself

Abstract

Previous work has demonstrated that variants of a heme protein,

Indexed as

biocatalystcarbenecytochrome cdirected evolutionlactonesorganoboron

Identifiers

PMID30930550
PMCPMC6436545
OpenAlexW2909057819

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.