Evidence map›Paper›PMID 30930445›Full record

ArticleAnatolian journal of cardiology2019

Higher ultrafiltration rate is associated with right ventricular mechanical dispersion.

Serkan Ünlü, Efstathios Pagourelias, Burak Sezenöz, Asife Şahinarslan, Orhan Mecit Uludağ, Gökhan Gökalp, Turgay Arınsoy, Atiye Çengel

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Article in Anatolian journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Serkan ÜnlüDepartment of Cardiology, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital; Ankara-Turkey.
Efstathios PagoureliasAristotle University of Thessaloniki, Hippokrateion University Hospital, Medical School, Third Cardiology Department; Thessaloniki-Greece.
Burak SezenözDepartment of Cardiology, Faculty of Medicine, Gazi University; Ankara-Turkey.
Asife ŞahinarslanDepartment of Cardiology, Faculty of Medicine, Gazi University; Ankara-Turkey.
Orhan Mecit UludağDepartment of Pharmacology, Faculty of Pharmacy, Gazi University; Ankara-Turkey.
Gökhan GökalpDepartment of Cardiology, Faculty of Medicine, Gazi University; Ankara-Turkey.
Turgay ArınsoyDepartment of Nephrology, Faculty of Medicine, Gazi University; Ankara-Turkey.
Atiye ÇengelDepartment of Cardiology, Faculty of Medicine, Gazi University; Ankara-Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveUltrafiltration rate is one of the major determinants of adverse outcomes in patients undergoing hemodialysis (HD) therapy. Previous studies have focused on the impact of HD on right ventricular (RV) peak strain values. However, the influence of HD on the temporal characteristics of deformation has not been reported yet. The aim of the present study was to evaluate the impact of high ultrafiltration rate (HUR) on RV mechanical dyssynchrony.

methodsEchocardiographic images focused on the RV and left ventricle (LV) were obtained from 60 patients (49.2+-17.3 years, 22 female) before and after HD. Patients were divided into two groups according to ultrafiltration rate. Changes in echocardiographic parameters with HD were examined. Two-dimensional speckle-tracking strain analysis was used to assess deformation. Mechanical dispersion was measured as the standard deviation of time to peak longitudinal strain of six segments for RV and 18 segments for LV.

resultsThe average ultrafiltrated volume and ultrafiltration rate were 3000.1+-1007.9 mL and 11.4+-2.9 mL/kg/h, respectively. Global longitudinal strain (GLS) of the RV and LV decreased after HD in both groups. A significant difference was observed in RV mechanical dispersion with HD for patients in the high ultrafiltration group. A mild statistically insignificant increase in LV mechanical dispersion was also observed after HD.

conclusionHUR has a substantial impact on LV and RV GLS and RV dyssynchrony. Ultrafiltration rates and volumes should be kept as low as possible to achieve hemodynamic stability and tolerability.

Indexed as

Renal DialysisCardiovascular DiseasesDiagnosis, DifferentialEchocardiographyFemaleHumansKidney Failure, ChronicMaleMiddle AgedUltrafiltrationVentricular Dysfunction, LeftVentricular Dysfunction, Right

Identifiers

PMID30930445
PMCPMC6528502

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