Evidence map›Paper›PMID 30930343›Full record

ArticleJournal of atherosclerosis and thrombosis2019

Arterial Stiffness and Endothelial Function in Young Obese Patients - Vascular Resistance Matters.

Barbora Czippelova, Zuzana Turianikova, Jana Krohova, Radovan Wiszt, Zuzana Lazarova, Katarina Pozorciakova, Miriam Ciljakova, Michal Javorka

Open access · diamondAbstract read
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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  13. Noninvasive arterial compliance estimation.Physiological research · 2021
    Review
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  16. The impacts of exercise on pediatric obesity.Clinical and experimental pediatrics · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Barbora CzippelovaComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Department of Physiology.
Zuzana TurianikovaComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Department of Physiology.
Jana KrohovaComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Department of Physiology.
Radovan WisztComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Department of Physiology.
Zuzana LazarovaComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Department of Physiology.
Katarina PozorciakovaComenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital Martin, Clinic of Children and Adolescents.
Miriam CiljakovaComenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital Martin, Clinic of Children and Adolescents.
Michal JavorkaComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Department of Physiology.
Comenius University Bratislava · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimMotivated by the paradoxical and differing results of the early atherosclerosis related indices - Cardio-Ankle Vascular Index (CAVI) reflecting arterial stiffness and Reactive Hyperemia Index (RHI) evaluating endothelium dependent flow-induced vasodilation - in obesity, we aimed to assess CAVI and RHI in obese adolescents and young adults in the context of differences in systemic vascular resistance (SVR).

methodsWe examined 29 obese (14f, 15.4 [12.3-18.5] y; BMI: 33.2±4.4 kg.m

resultsIn obese group, CAVI (4.59±0.88 vs. 5.18±0.63, p=0.002) and its refined version CAVI

conclusionOur results indicate that both indices used for the detection of early atherosclerotic changes are influenced by vascular tone. Vascular resistance could influence CAVI and RHI results impairing their interpretation.

Indexed as

HemodynamicsVascular ResistanceVascular StiffnessAdolescentAdultAnkle Brachial IndexAtherosclerosisBlood PressureCase-Control StudiesChildFemaleFollow-Up StudiesHumansMaleObesityPrognosisAdolescent obesityAtherosclerosisCardio-ankle vascular indexReactive hyperemia indexSympathetic activitySystemic vascular resistance

Identifiers

PMID30930343
PMCPMC6845697
OpenAlexW2930875052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.