Evidence map›Paper›PMID 30929904›Full record

ArticleCell2019

Shared Cortex-Cerebellum Dynamics in the Execution and Learning of a Motor Task.

Mark J Wagner, Tony Hyun Kim, Jonathan Kadmon, Nghia D Nguyen, Surya Ganguli, Mark J Schnitzer, Liqun Luo

Abstract read
In one paragraph

Article in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
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  7. Cerebellar microcircuits enable robust evidence-based decisions through cortico-cerebellar coupling.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
  9. Article
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Consensus Paper: Models of Cerebellar Functions.Cerebellum (London, England) · 2026
    Review
  17. Effects of Short-Term Synaptic Plasticity in Feedforward Inhibitory Circuits on Cerebellar Responses to Repetitive Sensory Input.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  18. Article
  19. Article
  20. Article

71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mark J WagnerDepartment of Biology, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address: mjwagner@stanford.edu.
Tony Hyun KimDepartment of Biology, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.
Jonathan KadmonDepartment of Applied Physics, Stanford University, Stanford, CA 94305, USA.
Nghia D NguyenDepartment of Biology, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Surya GanguliDepartment of Applied Physics, Stanford University, Stanford, CA 94305, USA.
Mark J SchnitzerDepartment of Biology, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA; Department of Applied Physics, Stanford University, Stanford, CA 94305, USA. Electronic address: mschnitz@stanford.edu.
Liqun LuoDepartment of Biology, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address: lluo@stanford.edu.

Funding

Mosaic Analysis with Double Markers in MiceR01NS050835 · NINDS · STANFORD UNIVERSITY · PI LIQUN LUO · 2005 to 2026
$7.3M
Neuromodulation of Brain StatesR01NS104698 · NINDS · STANFORD UNIVERSITY · PI LUO, LIQUN · 2018 to 2022
$3.3M
Howard Hughes Medical InstituteNINDS NIH HHS R01 NS050835NINDS NIH HHS R01 NS104698
6 · The paper itself

Abstract

Throughout mammalian neocortex, layer 5 pyramidal (L5) cells project via the pons to a vast number of cerebellar granule cells (GrCs), forming a fundamental pathway. Yet, it is unknown how neuronal dynamics are transformed through the L5→GrC pathway. Here, by directly comparing premotor L5 and GrC activity during a forelimb movement task using dual-site two-photon Ca

Indexed as

AnimalsBehavior, AnimalCalciumCerebellumForelimbMiceMice, TransgenicMicroscopy, Fluorescence, MultiphotonNeocortexOpsinsPyramidal CellsCalciumOpsinsbrain statecerebellumdimensional expansiongranule cellslayer 5motor learningmovement planningneocortexpontine nucleireward

Identifiers

PMID30929904
PMCPMC6500577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.