Trial reportBMC medicine2019
Improving engagement with healthcare in hepatitis C: a randomised controlled trial of a peer support intervention.
Trial report in BMC medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Do Peer Navigators Improve Initiation and Retention in HIV/VH/STI Treatment Programs for People From Key Populations? A Systematic Review of Effectiveness, Values and Preferences, and Cost.Journal of acquired immune deficiency syndromes (1999) · 2024Pooled it
- Barriers and facilitators to hepatitis C screening and treatment for people with lived experience of homelessness: A mixed-methods systematic review.Health expectations : an international journal of public participation in health care and health policy · 2022Pooled it
- Provision of peer support at the intersection of homelessness and problem substance use services: a systematic 'state of the art' review.BMC public health · 2020Pooled it
- Peer-assisted telemedicine for hepatitis C intervention in people experiencing housing instability.Harm reduction journal · 2026Trial
- Peer-Assisted Telemedicine for Hepatitis C in People Who Use Drugs: A Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Trial
- Nurse case management to improve the hepatitis C care continuum in HIV co-infection: Results of a randomized controlled trial.Journal of viral hepatitis · 2020Trial
- Peer advocacy and access to hospital care for people who are homeless in London, UK, 2019-2023: a cohort study.BMJ open · 2026Article
- Street-Based Hepatitis C Treatment and Patient Experiences Among Adults Experiencing Unsheltered Homelessness.JAMA network open · 2026Article
- Peer Interventions for Hepatitis C Testing and Treatment in OECD Countries: A Systematic Scoping Review.Journal of viral hepatitis · 2026Article
- Mapping experiences of workplace stigma and discrimination within the lived-living experience of illicit drug use and bloodborne virus peer workforce: a scoping review.Harm reduction journal · 2025Article
- Community engagement and chronic viral hepatitis public health interventions: a systematic review, meta-analysis, and complementary crowdsourcing open call.EClinicalMedicine · 2025Article
- Hepatitis C Care in the Greater New Orleans Area: Patient Perspectives on the Barriers and Facilitators to Care.Journal of health care for the poor and underserved · 2025Article
- Feasibility and effectiveness of a smartphone access program for promoting engagement in care among perinatal people with substance use disorders: a pilot study.Frontiers in health services · 2025Article
- Practical solutions to resolve social barriers to hepatitis C treatment initiation among people who inject drugs: a qualitative study.Harm reduction journal · 2024Article
- Article
- Prevalence of HCV Infection Among People Experiencing Homelessness in Madrid, Spain.JAMA network open · 2024Article
- Can you be a peer if you don't share the same health or social conditions? A qualitative study on peer integration in a primary care setting.BMC primary care · 2024Article
- Hepatitis B virus (HBV) screening, linkage and retention-in-care in inclusion health populations: Evaluation of an outreach screening programme in London.The Journal of infection · 2024Article
- Quality standards for the management of alcohol-related liver disease: consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology ARLD special interest group.BMJ open gastroenterology · 2023Article
- Realist review of community coalitions and outreach interventions to increase access to primary care for vulnerable populations: a realist review.Archives of public health = Archives belges de sante publique · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundPeer support can enable patient engagement with healthcare services, particularly for marginalised populations. In this randomised controlled trial, the efficacy of a peer support intervention at promoting successful engagement with clinical services for chronic hepatitis C was assessed.
methodsIn London, UK, potential participants were approached through outreach services for problematic drug use and homelessness. Individuals positive for hepatitis C virus (HCV) after confirmatory testing were randomised using an online service to the intervention (peer support) or standard of care. The primary outcome of interest was successful engagement with clinical hepatitis services. The study was non-blinded. Absolute differences were calculated using a generalised linear model and the results compared to logistic regression.
resultsThree hundred sixty-four individuals consented to participate. One hundred one had chronic hepatitis C and were randomised, 63 to receive the intervention (peer support). A successful outcome was achieved by 23 individuals in this arm (36.5%) and seven (18.4%) receiving the standard of care, giving an absolute increase of 18.1% (95% confidence interval 1.0-35.2%, p value = 0.04). This was mirrored in the logistic regression (odds ratio 2.55 (0.97-6.70), p = 0.06). No serious adverse events were reported.
conclusionsPeer support can improve the engagement of patients with chronic HCV with healthcare services.
trial registrationISRCTN24707359 . Registered 19th October 2012.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.