ArticlePaediatric anaesthesia2019
The Society for Pediatric Anesthesia recommendations for the use of opioids in children during the perioperative period.
Article in Paediatric anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06940570 (A Randomized Single Center Trial to Determine the Efficacy of Methadone as a First Line Agent in the Reduction and Treatment of Pain in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation), which is not on this map. Cited by 60 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Single Center Trial to Determine the Efficacy of Methadone as a First Line Agent in the Reduction and Treatment of Pain in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation
Who cites it
60 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Erector spinae plane block in pediatric surgery: a systematic review and meta-analysis.BMC anesthesiology · 2026Pooled it
- [Evidence-based guideline for neonatal pain management in China (2023)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Guideline
- Bilateral ultrasound-guided erector spinae plane block for postoperative analgesia in paediatric idiopathic scoliosis patients undergoing posterior spine fusion surgery: a randomized controlled trial.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Trial
- Effectiveness of perioperative low-dose esketamine infusion for postoperative pain management in pediatric urological surgery: a prospective clinical trial.BMC anesthesiology · 2024Trial
- Perspectives in Pediatric Ambulatory Anesthesia: Part 1-One Center's 15 Year Evolution in Eligibility, Utilization, Efficiency, and Outcomes.Paediatric anaesthesia · 2026Article
- Fascial plane blocks in pediatric patients.Journal of anesthesia, analgesia and critical care · 2026Review
- Comparative analysis of analgesic mechanisms in craniotomy pediatric patients: a scoping review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Rethinking postoperative opioid use in pediatric appendectomy: a cross-cultural comparison between Japan and North America.Journal of anesthesia · 2026Article
- Postoperative pain management in children.Frontiers in pediatrics · 2026Review
- Article
- Multi-Institutional Study of Multimodal Analgesia Practice, Pain Trajectories, and Recovery Trends After Spine Fusion for Idiopathic Scoliosis.Anesthesia and analgesia · 2025Article
- Best Evidence Summary for Perioperative Pain Management in Patients With Pectus Excavatum.Pain research & management · 2025Review
- Opioid versus Non-Opioid Postoperative Pain Management for Pediatric Supracondylar Humerus Fractures.The Iowa orthopaedic journal · 2025Article
- Ambulatory pediatric adenotonsillectomy.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Review
- Article
- Article
- Use of Biofeedback-Based Virtual Reality in Pediatric Perioperative and Postoperative Settings: Observational Study.JMIR perioperative medicine · 2024Article
- Factors Associated with Postoperative Opioid Use in Adolescents.Journal of pediatric surgery · 2024Article
- Ketorolac Dosing and Outcomes in Neonates Following Congenital Heart Surgery: A Retrospective Analysis.Critical care explorations · 2024Article
- Physiologically based modeling reveals different risk of respiratory depression after fentanyl overdose between adults and children.Clinical and translational science · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Opioids have long held a prominent role in the management of perioperative pain in adults and children. Published reports concerning the appropriate, and inappropriate, use of these medications in pediatric patients have appeared in various publications over the last 50 years. For this document, the Society for Pediatric Anesthesia appointed a taskforce to evaluate the available literature and formulate recommendations with respect to the most salient aspects of perioperative opioid administration in children. The recommendations are graded based on the strength of the available evidence, with consensus of the experts applied for those issues where evidence is not available. The goal of the recommendations was to address the most important issues concerning opioid administration to children after surgery, including appropriate assessment of pain, monitoring of patients on opioid therapy, opioid dosing considerations, side effects of opioid treatment, strategies for opioid delivery, and assessment of analgesic efficacy. Regular updates are planned with a re-release of guidelines every 2 years.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.