ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2019
Predictive factors associated with ventriculoperitoneal shunting after posterior fossa tumor surgery in children.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The role of external ventricular drainage for the management of posterior cranial fossa tumours: a systematic review.Neurosurgical review · 2021Pooled it
- PITCH (pediatric infratentorial tumors - hydrocephalus-related complications) registry study design: observational, prospective, multicenter study evaluating the number of surgeries associated with the treatment of hydrocephalus secondary to infratentorial tumors in childhood and adolescence.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Observational
- Predictors of pre-resection hydrocephalus in posterior cranial fossa tumors: development of a predictive scoring model.Neurosurgical review · 2025Article
- Validating the modified Canadian Preoperative Prediction Rule for Hydrocephalus for accurate hydrocephalus prediction in a statewide pediatric brain tumor cohort.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Transient and permanent hydrocephalus following resection of brain metastases located in the posterior fossa: incidence, risk factors and the necessity of perioperative external ventricular drainage placement.Journal of neuro-oncology · 2025Article
- Cerebrospinal fluid diversion prior to posterior fossa tumor resection in adults: A systematic review.Neuro-oncology practice · 2024Article
- Placement of EVD in pediatric posterior fossa tumors: safe and efficient or old-fashioned? The Vienna experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Perioperative external ventricular drainage vs. no-EVD strategy in pediatric posterior fossa tumors-pilot study results.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- A scoring system categorizing risk factors to evaluate the need for ventriculoperitoneal shunt in pediatric patients after brain tumor resection.Frontiers in oncology · 2023Article
- Posterior Fossa Tumours in the First Year of Life: A Two-Centre Retrospective Study.Diagnostics (Basel, Switzerland) · 2022Article
- Management of Posterior Fossa Tumors in Adults Based on the Predictors of Postoperative Hydrocephalus.Frontiers in surgery · 2022Article
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7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of the study was to evaluate established risk factors and define new inflammation-associated factors associated with postoperative ventriculoperitoneal shunt placement.
methodsThe electronic medical records of children who underwent surgery for a tumor in the posterior fossa between January 2009 and January 2018 were retrospectively analyzed. Factors evaluated include age, clinical symptoms, tumor type, extent of surgical tumor resection, treatment with EVD and/or ETV, radiological findings, postoperative serum CRP, and leucocyte levels. Tumor tissue was stained immunohistochemically with antibodies against CD3, and leucocyte counts were performed. Patients with pre- or postoperative signs of infection or confirmation of a concurrent infection were excluded from some analyses.
resultsSeventy patients ages 0.4-20.8 years (median, 8.2) were included. Forty-five of 70 (65.3%) presented postoperative radiological signs of hydrocephalus. Fifteen of 70 (21.4%) patients required shunt placement postoperatively. Shunt placement was significantly associated with age < 3 years at diagnosis (p = 0.013), perioperative EVD placement (p < 0.001), signs of hydrocephalus in postoperative imaging (p = 0.047), a frontooccipital horn ratio (FOHR) > 0.46 within the first 72 h postoperatively (p < 0.001), and the presence of intraventricular blood postoperatively (p = 0.007). Six patients who underwent shunting had serum CRP levels > 40 mg/l (p = 0.030) within the first 48 h postoperatively. Tumor type or extent of resection did not correlate with shunt placement.
conclusionsSeveral established and new factors associated with shunt placement after posterior fossa tumor surgery could be identified. Additional studies are needed to explore the aseptic inflammation pathways involved with increased CRP levels and shunt placement.
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