Evidence map›Paper›PMID 30929056›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2019

Audiological and vestibular measurements in Behçet's disease.

Ozlem Ertugrul, Ahmet Mutlu, Ilkin Zindanci, Osman Halit Cam, Levent Ozluoglu

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Analysis of sensorineural hearing loss and its relation to Optical Coherence Tomography Angiography findings in Behcet's disease.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ozlem ErtugrulAudiology Department, Goztepe Training and Research Hospital, Istanbul Medeniyet University, Istanbul, Turkey.
Ahmet MutluOtorhinolaryngology Department, Uskudar State Hospital, Barbaros Mahallesi, Veysi Pasa Sokak No. 14, Uskudar, 34672, Istanbul, Turkey. ahmutlu1988@gmail.com.ORCID http://orcid.org/0000-0001-9022-921X
Ilkin ZindanciDepartment of Dermatology, Umraniye Training and Research Hospital, School of Medicine, Medical Science University, Istanbul, Turkey.
Osman Halit CamOtorhinolaryngology Department, Istanbul Practice and Research Center, Medical Faculty, Baskent University, Istanbul, Turkey.
Levent OzluogluOtorhinolaryngology Department, Medical Faculty, Baskent University, Ankara, Turkey.
Başkent University · TRIstanbul Medeniyet University · TRÜmraniye Eğitim ve Araştırma Hastanesi · TRÜsküdar University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBehçet's disease (BD) is a vasculitis that involves all small vessels and influences the multiple systems of the human body. This study aimed to evaluate the audio-vestibular system involvement of patients with BD and healthy individuals. MATERIALS AND

methodsThis study was designed as a prospective case-control blinded study. Thirty-one patients with BD and 31 healthy individuals were included. All the subjects were evaluated via pure tone audiometry (PTA), video head impulse test (vHIT), post head shake nystagmus test (PHSNT) and dizziness handicap inventory (DHI) to check for audio-vestibular system involvement.

resultsPatients with BD showed higher PTA scores in both speech and high frequencies. The vHIT revealed pathological saccades, particularly in horizontal canals (right ear: p = 0.002, left ear: p = 0.039). The gain values of the patients were slightly lower than those of the control group; however, gain and gain asymmetry differed significantly in a few canals. In the spontaneous nystagmus test and PHSNT, pathological nystagmus was detected to be significantly higher in the patient group than control group (p = 0.001); but the saccade presence in vHIT and nystagmus in PHNT did not differ among the patients (p = 0.106). In addition, the DHI scores of the patients group were higher than those of the control group (p < 0.001). No correlation was found between disease duration and saccade presence.

conclusionThe vHIT was used preliminary for evaluating the vestibular system in BD. This study showed the influence of BD on the audio-vestibular system, in particular isolated horizontal canal involvement was discovered in patients with BD. LEVEL OF EVIDENCE: Level III b.

Indexed as

AdultAudiometry, Pure-ToneBehcet SyndromeCase-Control StudiesDizzinessFemaleHead Impulse TestHumansMaleMiddle AgedNystagmus, PathologicProspective StudiesReflex, Vestibulo-OcularRisk FactorsSaccadesSemicircular CanalsBehçet’s diseaseDizziness handicap inventoryNystagmusSemicircular canalsVestibulo-ocular reflexVideo head impulse test

Identifiers

PMID30929056
OpenAlexW2928507630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.