ArticleBMJ open2019
Risk of benign paroxysmal positional vertigo in patients with depressive disorders: a nationwide population-based cohort study.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Construction of a recurrence risk prediction model for benign paroxysmal positional vertigo.Acta neurologica Belgica · 2026Article
- Psychological Well-Being, Neuroticism, and the Risk of Benign Paroxysmal Positional Vertigo: A Triangulation Study.Brain and behavior · 2026Article
- Mendelian randomization analysis reveals causal relationship between depression, antidepressants and benign paroxysmal vertigo.Scientific reports · 2025Article
- Review
- Potential mechanisms of gut microbiota influence on different types of vertigo: a bidirectional Mendelian randomization and mediation analysis.BMC neurology · 2024Article
- Association between Benign Paroxysmal Positional Vertigo and Thyroid Diseases: Systematic Review and Meta-Analysis.International archives of otorhinolaryngology · 2024Review
- Development and verification of a nomogram for recurrence risk of Benign Paroxysmal Positional Vertigo in middle-aged and older populations.Frontiers in neurology · 2024Article
- The relationship between psychological conditions and recurrence of benign paroxysmal positional vertigo: a retrospective cohort study.BMC neurology · 2023Article
- The effect of accompanying anxiety and depression on patients with different vestibular syndromes.Frontiers in aging neuroscience · 2023Article
- What Predicts Improvement of Dizziness after Multimodal and Interdisciplinary Day Care Treatment?Journal of clinical medicine · 2022Article
- Predictive values of serum estradiol, calcium, and 25-hydroxyvitamin D levels for recurrence of benign paroxysmal positional vertigo in postmenopausal women.Turkish journal of physical medicine and rehabilitation · 2022Article
- Analyses of the Relation between BPPV and Thyroid Diseases: A Nested Case-Control Study.Diagnostics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe association between depression and benign paroxysmal positional vertigo (BPPV) remains debated. This study aimed to investigate the risk of BPPV in patients with depressive disorders.
designLongitudinal nationwide cohort study.
settingNational health insurance research database in Taiwan.
participantsWe enrolled 10 297 patients diagnosed with depressive disorders between 2000 and 2009 and compared them to 41 188 selected control patients who had never been diagnosed with depressive disorders (at a 1:4 ratio matched by age, sex and index date) in relation to the risk of developing BPPV.
methodsThe follow-up period was defined as the time from the initial diagnosis of depressive disorders to the date of BPPV, censoring or 31 December 2009. Cox proportional hazard regression analysis was used to investigate the risk of BPPV by sex, age and comorbidities, with HRs and 95% CIs.
resultsDuring the 9-year follow-up period, 44 (0.59 per 1000 person-years) patients with depressive disorders and 99 (0.33 per 1000 person-years) control patients were diagnosed with BPPV. The incidence rate ratio of BPPV among both cohorts calculating from events of BPPV per 1000 person-years of observation time was 1.79 (95% CI 1.23 to 2.58, p=0.002). Following adjustments for age, sex and comorbidities, patients with depressive disorders were 1.55 times more likely to develop BPPV (95% CI 1.08 to 2.23, p=0.019) as compared with control patients. In addition, hyperthyroidism (HR=3.75, 95% CI 1.67-8.42, p=0.001) and systemic lupus erythematosus (SLE) (HR=3.47, 95% CI 1.07 to 11.22, p=0.038) were potential risk factors for developing BPPV in patients with depressive disorders.
conclusionsPatients with depressive disorders may have an increased risk of developing BPPV, especially those who have hyperthyroidism and SLE.
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