ArticleJournal of psychiatric research2019
Distinct resting state functional connectivity abnormalities in hoarding disorder and major depressive disorder.
Article in Journal of psychiatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Repetitive transcranial magnetic stimulation (rTMS) for comorbid major depressive disorder and hoarding disorder: An open label pilot study.Journal of affective disorders · 2026Trial
- Changes in hoarding-related beliefs and associated neural changes during a simulated discarding task after cognitive-behavioral treatment for hoarding disorder.Journal of psychiatric research · 2024Article
- An exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder.Journal of affective disorders · 2024Article
- Reduced resting-state functional connectivity between insula and inferior frontal gyrus and superior temporal gyrus in hoarding disorder.Frontiers in psychiatry · 2024Article
- An Examination of the Association Between Subjective Distress and Functional Connectivity During Discarding Decisions in Hoarding Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
- Hoarding Disorder: Development in Conceptualization, Intervention, and Evaluation.Focus (American Psychiatric Publishing) · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Emerging research suggests that hoarding disorder (HD) is associated with abnormal hemodynamic activity in frontal brain regions. Prior studies have not examined intrinsic network connectivity in HD during unstructured "resting state" fMRI. Furthermore, it remains unclear whether previously observed HD abnormalities might be better explained by the presence of other disorders frequently comorbid with HD, such as major depressive disorder (MDD). The current study compared resting state functional connectivity in HD-only patients (n = 17), MDD-only patients (n = 8), patients with co-occurring HD and MDD (n = 10), and healthy control participants (n = 18). Using independent component analysis, we found that HD-only patients exhibited lower functional connectivity in a "task positive" cognitive control network, compared to the other three groups. The HD group also had greater connectivity in regions of the "task negative" default mode network than did the other groups. Findings suggest that HD is associated with a unique neurobiological profile, and are discussed in terms of recent neurological and neuropsychological findings and models in HD and related disorders.
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