Evidence map›Paper›PMID 30927348›Full record

ReviewMicrobiology spectrum2019

Zachary M Nash, Peggy A Cotter

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology spectrum, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. First inhibitor of a bacterial two-partner secretion system.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. mBio · 2024
    Article
  9. Article
  10. Review
  11. Deep longitudinal multi-omics analysis ofFrontiers in microbiology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zachary M NashDepartment of Microbiology and Immunology, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599.
Peggy A CotterDepartment of Microbiology and Immunology, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599.
University of North Carolina at Chapel Hill · US

Funding

PlrSR-dependent Signal Transduction in Bordetella VirulenceR01AI129541 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COTTER, PEGGY A · 2017 to 2021
$2.5M
NIAID NIH HHS R01 AI129541
6 · The paper itself

Abstract

Bacteria use a variety of mechanisms to translocate proteins from the cytoplasm, where they are synthesized, to the cell surface or extracellular environment or directly into other cells, where they perform their ultimate functions. Type V secretion systems (T5SS) use β-barrel transporter domains to export passenger domains across the outer membranes of Gram-negative bacteria. Distinct among T5SS are type Vb or two-partner secretion (TPS) systems in which the transporter and passenger are separate proteins, necessitating a mechanism for passenger-translocator recognition in the periplasm and providing the potential for reuse of the translocator. This review describes current knowledge of the TPS translocation mechanism, using

Indexed as

Adhesins, BacterialBacterial Outer Membrane ProteinsBordetellaBordetella pertussisGram-Negative BacteriaHemagglutininsMembrane Transport ProteinsModels, MolecularSecretory PathwayType V Secretion SystemsVirulenceVirulence Factors, BordetellaWhooping CoughAdhesins, BacterialBacterial Outer Membrane ProteinsfhaC protein, Bordetella pertussisfilamentous hemagglutinin adhesin, Bordetella pertussisHemagglutininsMembrane Transport ProteinsType V Secretion SystemsVirulence Factors, Bordetella

Identifiers

PMID30927348
PMCPMC6443250
OpenAlexW2933731149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.