Evidence map›Paper›PMID 30927179›Full record

ArticleJournal of autism and developmental disorders2019

Whole Blood Serotonin Levels and Platelet 5-HT

Elizabeth Aaron, Alicia Montgomery, Xinguo Ren, Stephen Guter, George Anderson, Ana M D Carneiro, Suma Jacob, Matthew Mosconi, Ghanshyam N Pandey, Edwin Cook and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Novel therapeutics in autism spectrum disorder.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Elizabeth AaronDepartment of Psychiatry, Columbia University Medical Center, 1051 Riverside Drive, Mail Unit 78, New York, NY, 10032, USA.
Alicia MontgomerySydney Children's Hospital, Community Health Center, High Street, Randwick, NSW, 2031, Australia.
Xinguo RenDepartment of Psychiatry, University of Illinois at Chicago, 1601 W. Taylor Street, Chicago, IL, 60612, USA.
Stephen GuterDepartment of Psychiatry, University of Illinois at Chicago, 1601 W. Taylor Street, Chicago, IL, 60612, USA.
George AndersonChild Study Center, Yale University, 230 South Frontage Rd, New Haven, CT, 06519, USA.
Ana M D CarneiroDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University School of Medicine, 465 21st Avenue South, Nashville, TN, 37232, USA.
Suma JacobDepartment of Psychiatry, University of Minnesota, 2450 Riverside Ave, Minneapolis, MN, 55454, USA.
Matthew MosconiDole Human Development Center, University of Kansas, 1000 Sunnyside Avenue, Lawrence, KS, 66045, USA.
Ghanshyam N PandeyDepartment of Psychiatry, University of Illinois at Chicago, 1601 W. Taylor Street, Chicago, IL, 60612, USA.
Edwin CookDepartment of Psychiatry, University of Illinois at Chicago, 1601 W. Taylor Street, Chicago, IL, 60612, USA.
Jeremy Veenstra-VanderWeeleDepartment of Psychiatry, Columbia University Medical Center, 1051 Riverside Drive, Mail Unit 78, New York, NY, 10032, USA. jeremy.veenstra-vanderweele@nyspi.columbia.edu.
University of Illinois Chicago · USNewYork–Presbyterian Hospital · USSydney Children's Hospital · AUUniversity of Kansas · USUniversity of Minnesota · USVanderbilt University · USYale University · US

Funding

Translational Research Training in Child PsychiatryT32MH016434 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Cristiane S. Duarte, Kate Dimond Fitzgerald · 1985 to 2026
$10.9M
TRANS STUDIES OF COGNITIVE,AFFECTIVE/NEUROCHEMICAL PROCESSES UNDERLYING INSISTENCP50HD055751 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI COOK, EDWIN H · 2007 to 2011
$9.5M
Expression and Methylation of HPA Axis Genes in Adult Suicide BrainR01MH106565 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PANDEY, GHANSHYAM N · 2016 to 2020
$2.7M
Neurobiological Signatures of Social Dysfunction and Repetitive BehaviorR01MH094604 · NIMH · VANDERBILT UNIVERSITY · PI VEENSTRA-VANDERWEELE, JEREMY · 2011 to 2015
$2.0M
National Institute of Child Health and Human Development HD055751NICHD NIH HHS P50 HD055751NIMH NIH HHS MH016434NIMH NIH HHS MH094604NIMH NIH HHS MH106565NIMH NIH HHS R01 MH094604NIMH NIH HHS R01 MH106565NIMH NIH HHS T32 MH016434Simons Foundation Autism Research Initiative Simplex Project
6 · The paper itself

Abstract

Elevated whole blood serotonin (WB5-HT) is a well-replicated biomarker in autism spectrum disorder (ASD). Decreased platelet serotonin receptor 5-HT

Indexed as

Autism Spectrum DisorderBiomarkersBlood PlateletsChildChild, PreschoolFemaleHumansMaleProtein BindingReceptor, Serotonin, 5-HT2ASerotoninBiomarkersReceptor, Serotonin, 5-HT2ASerotoninAutism spectrum disorderBiomarkerHyperserotonemiaReceptorSerotonin

Identifiers

PMID30927179
PMCPMC6549243
OpenAlexW2927650891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.