ArticleEsophagus : official journal of the Japan Esophageal Society2019
Obesity and hiatal hernia may be non-allergic risk factors for esophageal eosinophilia in Japanese adults.
Article in Esophagus : official journal of the Japan Esophageal Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Burden of Eosinophilic Esophagitis and Gastroesophageal Reflux Disease in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Comprehensive US Healthcare Analysis.Journal of gastroenterology and hepatology · 2026Article
- Review
- Weight Gain Is Associated With Decreased Treatment Response to Dietary Therapy in Adults With Eosinophilic Esophagitis.Gastro hep advances · 2025Article
- Long-term course of untreated asymptomatic esophageal eosinophilia and minimally symptomatic eosinophilic esophagitis.Endoscopy international open · 2024Article
- Higher Body Mass Index Is Associated With Decreased Treatment Response to Topical Steroids in Eosinophilic Esophagitis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Article
- Possible role of insulin resistance in activation of plasma xanthine oxidoreductase in health check-up examinees.Scientific reports · 2022Observational
- Clinicopathological Differences between Eosinophilic Esophagitis and Asymptomatic Esophageal Eosinophilia.Internal medicine (Tokyo, Japan) · 2022Article
- Subjective Symptoms in Patients with Eosinophilic Esophagitis Are Related to Esophageal Wall Thickness and Esophageal Body Pressure.Digestive diseases and sciences · 2021Article
- Eosinophilic esophagitis and asymptomatic esophageal eosinophilia display similar immunohistological profiles.Journal of clinical biochemistry and nutrition · 2021Article
- Vonoprazan shows efficacy similar to that of proton pump inhibitors with respect to symptomatic, endoscopic, and histological responses in patients with eosinophilic esophagitis.Esophagus : official journal of the Japan Esophageal Society · 2021Article
- Uric acid shown to contribute to increased oxidative stress level independent of xanthine oxidoreductase activity in MedCity21 health examination registry.Scientific reports · 2021Article
- Immunohistochemical expression of filaggrin is decreased in proton pump inhibitor non-responders compared with proton pump inhibitor responders of eosinophilic esophagitis.Esophagus : official journal of the Japan Esophageal Society · 2021Article
- Malnutrition in Eosinophilic Gastrointestinal Disorders.Nutrients · 2020Review
- Symptom-based diagnostic approach for eosinophilic esophagitis.Journal of gastroenterology · 2020Review
- Association of plasma xanthine oxidoreductase activity with blood pressure affected by oxidative stress level: MedCity21 health examination registry.Scientific reports · 2020Article
- Eosinophilic esophagitis: time for clinical practice.Esophagus : official journal of the Japan Esophageal Society · 2019Article
- Insulin Resistance Associated with Plasma Xanthine Oxidoreductase Activity Independent of Visceral Adiposity and Adiponectin Level: MedCity21 Health Examination Registry.International journal of endocrinology · 2019Article
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Authors and funding
17 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEsophageal eosinophilia (EE) is a basal condition of eosinophilic esophageal disorders including eosinophilic esophagitis (EoE) and asymptomatic EE. EoE is considered as an allergic disorder, while it is unclear whether other non-allergic conditions are involved in the pathophysiology of EE. The aim of this study is to investigate the non-allergic risk factors for EE.
methodsThis cross-sectional study included subjects who underwent esophagogastroduodenoscopy on a medical health check-up. We compared clinical characteristics between subjects with EE (n = 27) and those without EE (n = 5937).
resultsThe detection rate of EE was 0.45% (27/5964 persons). Of 27 subjects with EE, 20 subjects were symptomatic and 7 were asymptomatic. On univariate analysis, subjects with EE significantly had higher body mass index (BMI) compared to those without EE; 23.4 (4.4) vs 22.3 (4.5) kg/m
conclusionsObesity and hiatal hernia may be non-allergic risk factors for EE in Japanese adults.
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