ArticleAnnals of intensive care2019
Gender and survival of critically ill patients: results from the FROG-ICU study.
Article in Annals of intensive care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01367093 (French and EuRopean Outcome Registry in Intensive Care Unit), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
French and EuRopean Outcome Registry in Intensive Care Unit
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Factors associated with mortality in patients with COVID-19 admitted to intensive care: a systematic review and meta-analysis.Anaesthesia · 2021Pooled it
- Sex, time, and disability status differences in mortality, multidimensional morbidity, and health care utilization: a secondary analysis of the Canadian RECOVER study.Intensive care medicine · 2026Article
- Gender-Based Differences in COPD Patients with Type 2 Respiratory Failure-Impact on Clinical Practice.Medicina (Kaunas, Lithuania) · 2025Observational
- Sex specific differences in short-term mortality after ICU-delirium.Critical care (London, England) · 2024Article
- Sex differences in the use of mechanical ventilation in a neurointensive care population: a retrospective study.BMC pulmonary medicine · 2024Article
- Sex and gender differences in intensive care medicine.Intensive care medicine · 2023Review
- Sex-specific outcomes in COVID-19: missing pieces of the puzzle.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Article
- Review
- Association between early nutrition support and 28-day mortality in critically ill patients: the FRANS prospective nutrition cohort study.Critical care (London, England) · 2023Article
- Sex Differences in Mortality of ICU Patients According to Diagnosis-related Sex Balance.American journal of respiratory and critical care medicine · 2022Article
- Sex-specific treatment characteristics and 30-day mortality outcomes of critically ill COVID-19 patients over 70 years of age-results from the prospective COVIP study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Article
- Outcomes of Patients With Primary Cardiac Diagnoses Admitted to Cardiac vs Noncardiac Intensive Care Units.JACC. Advances · 2022Article
- Time to recovery and its predictors among critically ill patients on mechanical ventilation from intensive care unit in Ethiopia: a retrospective follow up study.BMC emergency medicine · 2022Article
- Gender-Specific Differences in the Intensive Care Treatment of COVID-19 Patients.Journal of personalized medicine · 2022Article
- Sex Differences in Clinical Characteristics and Outcomes of Patients with SARS-CoV-2-Infection Admitted to Intensive Care Units in Austria.Journal of personalized medicine · 2022Article
- Sex-Specific Aspects of Skeletal Muscle Metabolism in the Clinical Context of Intensive Care Unit-Acquired Weakness.Journal of clinical medicine · 2022Article
- Acute renal replacement therapy in critically ill octogenarian or older patients: prognostic factors and renal outcomes.Journal of nephrology · 2021Article
- Gender Differences in Critical Illness and Critical Care Research.Clinics in chest medicine · 2021Review
- Article
- Sex differences in intensive care unit admissions in Australia and New Zealand.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2021Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
purposeFew studies analyzed gender-related outcome differences of critically ill patients and found inconsistent results. This study aimed to test the independent association of gender and long-term survival of ICU patients. MATERIALS AND
methodsFROG-ICU was a prospective, observational, multi-center cohort designed to investigate the long-term mortality of critically ill adult patients. The primary endpoint of this study was 1-year mortality after ICU admission of women compared to men.
resultsThe study included 2087 patients, 726 women and 1361 men. Women and men had similar baseline characteristics, clinical presentation, and disease severity. No significant difference in 1-year mortality was found between women and men (34.9% vs. 37.9%, P = 0.18). After multivariable adjustment, no difference in the hazard of death was observed [HR 0.99 (95% CI 0.77-1.28)]. Similar 1-year survival between women and men was found in a propensity score-matched patient cohort of 506 patients [HR 0.79 (95% CI 0.54-1.14)].
conclusionWomen constituted one-third of the population of critically ill patients and were unexpectedly similar to men regarding demographic characteristics, clinical presentation, and disease severity and had similar risk of death at 1 year after ICU admission. Trial registration ClinicalTrials.gov NCT01367093; registered on June 6, 2011.
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