Evidence map›Paper›PMID 30927017›Full record

ArticleCellular and molecular life sciences : CMLS2019

Cdc14 activation requires coordinated Cdk1-dependent phosphorylation of Net1 and PP2A-Cdc55 at anaphase onset.

Soraya Játiva, Ines Calabria, Yolanda Moyano-Rodriguez, Patricia Garcia, Ethel Queralt

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. The Multiple Roles of the Cdc14 Phosphatase in Cell Cycle Control.International journal of molecular sciences · 2020
    Review
  9. PP2A Functions during Mitosis and Cytokinesis in Yeasts.International journal of molecular sciences · 2019
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Soraya JátivaCell Cycle Group, Cancer Epigenetics and Biology Program (PEBC), Institut d'Investigacions Biomèdica de Bellvitge (IDIBELL), Av. Gran Via de L'Hospitalet 199-203, 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
Ines CalabriaCell Cycle Group, Cancer Epigenetics and Biology Program (PEBC), Institut d'Investigacions Biomèdica de Bellvitge (IDIBELL), Av. Gran Via de L'Hospitalet 199-203, 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
Yolanda Moyano-RodriguezCell Cycle Group, Cancer Epigenetics and Biology Program (PEBC), Institut d'Investigacions Biomèdica de Bellvitge (IDIBELL), Av. Gran Via de L'Hospitalet 199-203, 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
Patricia GarciaCell Cycle Group, Cancer Epigenetics and Biology Program (PEBC), Institut d'Investigacions Biomèdica de Bellvitge (IDIBELL), Av. Gran Via de L'Hospitalet 199-203, 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
Ethel QueraltCell Cycle Group, Cancer Epigenetics and Biology Program (PEBC), Institut d'Investigacions Biomèdica de Bellvitge (IDIBELL), Av. Gran Via de L'Hospitalet 199-203, 08908, L'Hospitalet de Llobregat, Barcelona, Spain. equeralt@idibell.cat.ORCID http://orcid.org/0000-0003-0045-0039
Institut d'Investigació Biomédica de Bellvitge · ES

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España BFU2016-77975-RMinisterio de Economía y Competitividad BFU2013-43132-P
6 · The paper itself

Abstract

Exit from mitosis and completion of cytokinesis require the inactivation of mitotic cyclin-dependent kinase (Cdk) activity. In budding yeast, Cdc14 phosphatase is a key mitotic regulator that is activated in anaphase to counteract Cdk activity. In metaphase, Cdc14 is kept inactive in the nucleolus, where it is sequestered by its inhibitor, Net1. At anaphase onset, downregulation of PP2A

Indexed as

AnaphaseCDC28 Protein Kinase, S cerevisiaeCDC2 Protein KinaseCell Cycle ProteinsCell NucleusChromatography, High Pressure LiquidHumansMitosisNuclear ProteinsPhosphopeptidesPhosphorylationProtein Phosphatase 2Protein Tyrosine PhosphatasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSeparaseCDC14 protein, S cerevisiaeCDC28 Protein Kinase, S cerevisiaeCDC2 Protein KinaseCDC55 protein, S cerevisiaeCell Cycle ProteinsNet1 protein, S cerevisiaeNuclear ProteinsPhosphopeptidesProtein Phosphatase 2Protein Tyrosine PhosphatasesSaccharomyces cerevisiae ProteinsSeparaseCell cycleFEARMitosisMitotic exitPhosphatasesPP2A–Cdc55SeparaseZds1

Identifiers

PMID30927017
PMCPMC11105415
OpenAlexW2926190158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.