ArticleNature genetics2019
Transposable elements drive widespread expression of oncogenes in human cancers.
Erratum issuedAbstract read
In one paragraph
Article in Nature genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 231 papers.
0numbers the graph read from it
0cells of the map it votes in
231citing papers in PubMed
19.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
231 citing papers in PubMed, 409 citations in OpenAlex.
- The therapeutic potential of transposable element activity modulation.EMBO molecular medicine · 2026Review
- Exploring the Role of DNA Methylation in the Epigenetic Landscape of Cancer.Biochemical genetics · 2026Review
- Transposable Element Activation: A Hallmark of Cancer.Cancer discovery · 2026Review
- Differential Expression and Co-Variation of HERV-Associated Transcripts, IL-17 Cytokines, and NFκB in Paired Colorectal Cancer Tissues.Biomedicines · 2026Article
- Recurrent ZC3H18 mutations stabilize oncogenic endogenous retroviral RNA.Cell reports · 2026Article
- Decoding neoantigen-encoding tumor-specific transcripts unveils a shared target reservoir for immunotherapy in hepatocellular carcinoma.Journal for immunotherapy of cancer · 2026Article
- TIPs: a deep learning-guided proteogenomic framework to expand the landscape of transposable element-derived antigens with immunopeptidomics.Genome biology · 2026Article
- Gene body methylation suppresses intragenic transcription and permits epigenetic inheritance in a cnidarian.Nature ecology & evolution · 2026Article
- Transcriptional Activation of Transposable Element (TE)-Associated Genes Is Frequently Associated with Altered Promoter Methylation in Placenta and Melanoma.International journal of molecular sciences · 2026Article
- LINE-1 retrotransposons: Multifaceted functions and regulatory mechanisms in health and disease.Molecular therapy. Nucleic acids · 2026Review
- Review
- Transposable elements in hematopoietic stem cells upon aging and myeloid malignancies.Mobile DNA · 2026Review
- Embryonic stem cell factors DPPA2/4 amplify active H3K4me3-H2AK119ub chromatin domains in non-small cell lung cancer.Genes & development · 2026Article
- Unannotated noncoding transcripts as a source of intratumor heterogeneity in malignant cell states.Science China. Life sciences · 2026Article
- Transposable elements shape stemness in normal and leukemic hematopoiesis.Nature genetics · 2026Article
- Epigenetic Deregulation of Transposable Elements Links Developmental Processes and Tumorigenesis.International journal of molecular sciences · 2026Review
- TEffectBayes: a nextflow pipeline for exploring the potential effect of transposable elements in gene regulatory network with multi-omic Bayesian network model.Molecular genetics and genomics : MGG · 2026Article
- Analysis of HERV-K (HML2) Expression in Colorectal Cancer Samples.Epigenomes · 2026Article
- Viral mimicry acts as a tumor suppressor in colitis.Nature communications · 2026Article
- Stable genome structures in living fossil fishes.Genome research · 2026Article
171 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
13 authors at 1 institution in 1 country.
Hyo Sik Jang *Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0001-9654-4448
Nakul M Shah *Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Alan Y DuDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Zea Z DaileyDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Erica C PehrssonDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Paula M GodoyDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
David ZhangDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Daofeng LiDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Xiaoyun XingDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Sungsu KimDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
David O'DonnellDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Jeffrey I GordonDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Ting WangDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA. twang@wustl.edu.ORCID http://orcid.org/0000-0002-6800-242X
Washington University in St. Louis · US
Funding
TRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGYT32GM007067 · NIGMS · WASHINGTON UNIVERSITY · PI TRUE-KROB, HEATHER L · 1985 to 2020
$20.4MINSTITUTIONAL TRAINING GRANT IN GENOMIC SCIENCET32HG000045 · NHGRI · WASHINGTON UNIVERSITY · PI MICHAEL R BRENT, Barak A Cohen · 1997 to 2026
$8.4MTHE WASHU TARGET ENVIRONMENTAL EPIGENOMICS DATA COORDINATION CENTERU24ES026699 · NIEHS · WASHINGTON UNIVERSITY · PI WANG, TING · 2016 to 2021
$5.2MRESEARCH EDUCATION PROGRAM ON COMPUTATIONAL AND STATISTICAL TOOL DEVELOPMENT FOR ADDICTION GENETICSR25DA027995 · NIDA · WASHINGTON UNIVERSITY · PI MADDEN, PAMELA ANN, RICE, JOHN P. · 2009 to 2019
$4.3MDECODING THE IMPACT OF TRANSPOSABLE ELEMENTS ON GENE REGULATIONR01HG007175 · NHGRI · WASHINGTON UNIVERSITY · PI WANG, TING · 2014 to 2021
$2.7MConnecting transposable elements and regulatory innovation using ENCODE dataU01HG009391 · NHGRI · WASHINGTON UNIVERSITY · PI COHEN, BARAK A, FESCHOTTE, CEDRIC · 2017 to 2021
$2.4MANIMAL SUPPORT SPACE FOR NEUROSCIENCEC06RR015502 · NCRR · WASHINGTON UNIVERSITY · PI CICERO, THEODORE J · 2000 to 2000
$2.0MThe WashU 4DN Network Data Coordination and Integration CenterU01CA200060 · NCI · WASHINGTON UNIVERSITY · PI WANG, TING · 2015 to 2019
$1.9MADVANCED EPI/GENOME BROWSER WITH ENHANCED VISUALIZATION AND ANALYSIS TOOLSR01HG007354 · NHGRI · WASHINGTON UNIVERSITY · PI WANG, TING · 2013 to 2016
$1.5MCHARTING THE EPIGENOMIC LANDSCAPE OF HUMAN TRANSPOSABLE ELEMENTSR01ES024992 · NIEHS · WASHINGTON UNIVERSITY · PI WANG, TING · 2014 to 2015
$342kNCI NIH HHS U01 CA200060NCRR NIH HHS C06 RR015502NHGRI NIH HHS R01 HG007175NHGRI NIH HHS R01 HG007354NHGRI NIH HHS T32 HG000045NHGRI NIH HHS U01 HG009391NIDA NIH HHS R25 DA027995NIEHS NIH HHS R01 ES024992NIEHS NIH HHS U24 ES026699NIGMS NIH HHS T32 GM007067
Abstract
Transposable elements (TEs) are an abundant and rich genetic resource of regulatory sequences
Indexed as
Cell LineCell Line, TumorDNA MethylationDNA Transposable ElementsEvolution, MolecularHEK293 CellsHumansK562 CellsNeoplasmsOncogenesPromoter Regions, GeneticRegulatory Sequences, Nucleic AcidDNA Transposable Elements
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.