ArticleNature communications2019
The architecture of functional lateralisation and its relationship to callosal connectivity in the human brain.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 6 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
124 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- GINNA, a 33 resting-state networks atlas with meta-analytic decoding-based cognitive characterization.Communications biology · 2025Pooled it
- Sex differences in brain homotopic co-activations: a meta-analytic study.Brain structure & function · 2022Pooled it
- Pooled it
- White matter variability, cognition, and disorders: a systematic review.Brain structure & function · 2022Pooled it
- Handedness and midsagittal corpus callosum morphology: a meta-analytic evaluation.Brain structure & function · 2022Pooled it
- Functional neuroanatomy of language without speech: An ALE meta-analysis of sign language.Human brain mapping · 2021Pooled it
- Subacute changes in brain functional network connectivity after nocturnal sodium oxybate intake are associated with anterior cingulate GABA.Cerebral cortex (New York, N.Y. : 1991) · 2023Trial
- Intermittent theta burst stimulation over the parietal cortex has a significant neural effect on working memory.Human brain mapping · 2022Trial
- Hemispheric imbalance in mild cognitive impairment: a graph-theoretical analysis of multimodal brain networks.Annals of medicine · 2026Article
- Pallidal and subthalamic stimulations modulate inter-hemispheric interaction and asymmetry in Parkinson's disease.Molecular psychiatry · 2026Article
- Variations of global brain asymmetry are associated with aging and related diseases.Science advances · 2026Article
- Language laterality and cognitive skills: does anatomy matter?Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Manifold lateralisation and variability in the language connectome at 7T.Research square · 2026Article
- Mapping corpus callosum architecture: developmental, genetic, and cognitive correlates in youth.bioRxiv : the preprint server for biology · 2026Article
- Developmental disinhibition gates language lateralization in childhood.Nature communications · 2026Article
- Dorsolateral prefrontal cortex hemispheric asymmetry and chronic low back pain at 8-year follow-up in community-dwelling older adults.GeroScience · 2026Article
- Bridging Continuous and Discrete Models of the Anterior Temporal Lobe via Cortical Gradients.Research square · 2026Article
- Bridging glucose metabolism and intrinsic functional organization of the human cortex.Communications biology · 2026Article
- Cross-species lesion mapping links a midbrain circuit to vergence dysfunction.Brain : a journal of neurology · 2026Article
- Hemispheric disparity theory: a dual-system framework for consciousness.Frontiers in psychology · 2026Article
64 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Functional lateralisation is a fundamental principle of the human brain. However, a comprehensive taxonomy of functional lateralisation and its organisation in the brain is missing. Here, we report the first complete map of functional hemispheric asymmetries in the human brain, reveal its low dimensional structure, and its relationship with structural inter-hemispheric connectivity. Our results suggest that the lateralisation of brain functions is distributed along four functional axes: symbolic communication, perception/action, emotion, and decision-making. The similarity between this finding and recent work on neurological symptoms give rise to new hypotheses on the mechanisms that support brain recovery after a brain lesion. We also report that cortical regions showing asymmetries in task-evoked activity have reduced connections with the opposite hemisphere. This latter result suggests that during evolution, brain size expansion led to functional lateralisation to avoid excessive conduction delays between the hemispheres.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.