ArticleNature communications2019
Intrinsic functional architecture of the non-human primate spinal cord derived from fMRI and electrophysiology.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Neural Network Connection Characteristics Between Motor Cortex and Spinal Cord During Rat Bipedal Walking.CNS neuroscience & therapeutics · 2026Article
- A Hybrid RF Coil for Whole-Brain Imaging in Non-Human Primates at 7 T.Magnetic resonance in medicine · 2026Article
- Mapping Human Proprioceptive Projections of Upper Limb Muscles Through Spinal Cord fMRI.Human brain mapping · 2025Article
- Relationships Between Intra-Spinal Resting-State Functional Connectivity and Electrophysiology Following Spinal Cord Injury.Human brain mapping · 2025Article
- Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research.Neuropsychiatric disease and treatment · 2025Review
- EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Characteristic BOLD signals are detectable in white matter of the spinal cord at rest and after a stimulus.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Recent developments and future avenues for human corticospinal neuroimaging.Frontiers in human neuroscience · 2024Review
- Lumbosacral spinal cord functional connectivity at rest: From feasibility to reliability.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Article
- Spinal Cord fMRI: A New Window into the Central Nervous System.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2023Review
- Longitudinal multiparametric MRI of traumatic spinal cord injury in animal models.Magnetic resonance imaging · 2023Review
- Reliability of resting-state functional connectivity in the human spinal cord: Assessing the impact of distinct noise sources.NeuroImage · 2023Article
- Detection and characterization of resting state functional networks in squirrel monkey brain.Cerebral cortex communications · 2023Article
- Review
- Advanced spinal cord MRI in multiple sclerosis: Current techniques and future directions.NeuroImage. Clinical · 2022Review
- Article
- Article
- Spontaneous Multimodal Neural Transmission Suggests That Adult Spinal Networks Maintain an Intrinsic State of Readiness to Execute Sensorimotor Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- A Suite of Neurophotonic Tools to Underpin the Contribution of Internal Brain States in fMRI.Current opinion in biomedical engineering · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Resting-state functional MRI (rsfMRI) has recently revealed correlated signals in the spinal cord horns of monkeys and humans. However, the interpretation of these rsfMRI correlations as indicators of functional connectivity in the spinal cord remains unclear. Here, we recorded stimulus-evoked and spontaneous spiking activity and local field potentials (LFPs) from monkey spinal cord in order to validate fMRI measures. We found that both BOLD and electrophysiological signals elicited by tactile stimulation co-localized to the ipsilateral dorsal horn. Temporal profiles of stimulus-evoked BOLD signals covaried with LFP and multiunit spiking in a similar way to those observed in the brain. Functional connectivity of dorsal horns exhibited a U-shaped profile along the dorsal-intermediate-ventral axis. Overall, these results suggest that there is an intrinsic functional architecture within the gray matter of a single spinal segment, and that rsfMRI signals at high field directly reflect this underlying spontaneous neuronal activity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.