ArticleNature communications2019
Assembly of complex viruses exemplified by a halophilic euryarchaeal virus.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Article
- Article
- Glycoproteins in Viruses.Methods in molecular biology (Clifton, N.J.) · 2025Review
- The Expanding Diversity of Viruses from Extreme Environments.International journal of molecular sciences · 2024Review
- Integrative Approaches to Study Virus Structures.Sub-cellular biochemistry · 2024Review
- Cellular homologs of the double jelly-roll major capsid proteins clarify the origins of an ancient virus kingdom.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The LUCA and its complex virome.Nature reviews. Microbiology · 2020Review
- Superimposition of Viral Protein Structures: A Means to Decipher the Phylogenies of Viruses.Viruses · 2020Review
- Surface stresses in complex viral capsids and non-quasi-equivalent viral architectures.Journal of the Royal Society, Interface · 2020Article
- Global Organization and Proposed Megataxonomy of the Virus World.Microbiology and molecular biology reviews : MMBR · 2020Review
- Cryo-electron microscopy for the study of virus assembly.Nature chemical biology · 2020Review
- A packing for A-form DNA in an icosahedral virus.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Asymmetric analysis reveals novel virus capsid features.Biophysical reviews · 2019Review
- Structures of enveloped virions determined by cryogenic electron microscopy and tomography.Advances in virus research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Many of the largest known viruses belong to the PRD1-adeno structural lineage characterised by conserved pseudo-hexameric capsomers composed of three copies of a single major capsid protein (MCP). Here, by high-resolution cryo-EM analysis, we show that a class of archaeal viruses possess hetero-hexameric MCPs which mimic the PRD1-adeno lineage trimer. These hetero-hexamers are built from heterodimers and utilise a jigsaw-puzzle system of pegs and holes, and underlying minor capsid proteins, to assemble the capsid laterally from the 5-fold vertices. At these vertices proteins engage inwards with the internal membrane vesicle whilst 2-fold symmetric horn-like structures protrude outwards. The horns are assembled from repeated globular domains attached to a central spine, presumably facilitating multimeric attachment to the cell receptor. Such viruses may represent precursors of the main PRD1-adeno lineage, similarly engaging cell-receptors via 5-fold spikes and using minor proteins to define particle size.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.