Evidence map›Paper›PMID 30926786›Full record

ArticleNature communications2019

Exploring the colloid-to-polymer transition for ultra-low crosslinked microgels from three to two dimensions.

A Scotti, S Bochenek, M Brugnoni, M A Fernandez-Rodriguez, M F Schulte, J E Houston, A P H Gelissen, I I Potemkin, L Isa, W Richtering

Abstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Comparing the Structure of Microgels at Liquid-Liquid and Solid-Liquid Interfaces.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  8. Article
  9. Hydrogels and nanogels: effectiveness in dermal applications.Beilstein journal of nanotechnology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Soft colloids for complex interfacial assemblies.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  15. Article
  16. Defined core-shell particles as the key to complex interfacial self-assembly.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  17. Article
  18. Article
  19. Stiffness Tomography of Ultra-Soft Nanogels by Atomic Force Microscopy.Angewandte Chemie (International ed. in English) · 2021
    Article
  20. Lectin andMolecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

A ScottiInstitute of Physical Chemistry, RWTH Aachen University, 52056, Aachen, Germany. andrea.scotti@rwth-aachen.de.ORCID http://orcid.org/0000-0002-8988-330X
S BochenekInstitute of Physical Chemistry, RWTH Aachen University, 52056, Aachen, Germany.
M BrugnoniInstitute of Physical Chemistry, RWTH Aachen University, 52056, Aachen, Germany.ORCID http://orcid.org/0000-0003-2220-3645
M A Fernandez-RodriguezLaboratory for Interfaces, Soft Matter and Assembly, Department of Materials, ETH Zurich, 8093, Zurich, Switzerland.
M F SchulteInstitute of Physical Chemistry, RWTH Aachen University, 52056, Aachen, Germany.ORCID http://orcid.org/0000-0002-9411-242X
J E HoustonJülich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ) Forschungszentrum Jülich GmbH, 85748, Garching, Germany.ORCID http://orcid.org/0000-0001-5205-3620
A P H GelissenInstitute of Physical Chemistry, RWTH Aachen University, 52056, Aachen, Germany.
I I PotemkinPhysics Department, Lomonosov Moscow State University, 119991, Moscow, Russian Federation.
L IsaLaboratory for Interfaces, Soft Matter and Assembly, Department of Materials, ETH Zurich, 8093, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-6731-9620
W RichteringInstitute of Physical Chemistry, RWTH Aachen University, 52056, Aachen, Germany. richtering@rwth-aachen.de.ORCID http://orcid.org/0000-0003-4592-8171

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microgels are solvent-swollen nano- and microparticles that show prevalent colloidal-like behavior despite their polymeric nature. Here we study ultra-low crosslinked poly(N-isopropylacrylamide) microgels (ULC), which can behave like colloids or flexible polymers depending on dimensionality, compression or other external stimuli. Small-angle neutron scattering shows that the structure of the ULC microgels in bulk aqueous solution is characterized by a density profile that decays smoothly from the center to a fuzzy surface. Their phase behavior and rheological properties are those of soft colloids. However, when these microgels are confined at an oil-water interface, their behavior resembles that of flexible macromolecules. Once monolayers of ultra-low crosslinked microgels are compressed, deposited on solid substrate and studied with atomic-force microscopy, a concentration-dependent topography is observed. Depending on the compression, these microgels can behave as flexible polymers, covering the substrate with a uniform film, or as colloidal microgels leading to a monolayer of particles.

Identifiers

PMID30926786
PMCPMC6441029

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.