Evidence map›Paper›PMID 30926771›Full record

ArticleBlood cancer journal2019

Inhibition of the STAT3 target SGK1 sensitizes diffuse large B cell lymphoma cells to AKT inhibitors.

Li Lu, Fen Zhu, Yangguang Li, Shuichi Kimpara, Nguyet Minh Hoang, Sheida Pourdashti, Lixin Rui

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood cancer journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. EGR1 Addiction in Diffuse Large B-cell Lymphoma.Molecular cancer research : MCR · 2021
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Li LuDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA.ORCID http://orcid.org/0000-0003-0490-7163
Fen ZhuDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA.
Yangguang LiDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA.
Shuichi KimparaDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA.
Nguyet Minh HoangDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA.
Sheida PourdashtiDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA.
Lixin RuiDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA. lrui@medicine.wisc.edu.
University of Wisconsin–Madison · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Epigenetic Gene Regulation by JAK1 Kinase in Diffuse Large B-Cell LymphomaR01CA187299 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI RUI, LIXIN · 2015 to 2019
$1.7M
NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA187299
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansLymphoma, Large B-Cell, DiffuseProtein Kinase InhibitorsSTAT3 Transcription FactorProtein Kinase InhibitorsSTAT3 protein, humanSTAT3 Transcription Factor

Identifiers

PMID30926771
PMCPMC6441016
OpenAlexW2927193548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.