Evidence map›Paper›PMID 30926737›Full record

ArticleGlobal health, science and practice2019

Successfully Engaging Private Providers to Improve Diagnosis, Notification, and Treatment of TB and Drug-Resistant TB: The EQUIP Public-Private Model in Chennai, India.

Ramya Ananthakrishnan, M D'Arcy Richardson, Susan van den Hof, Radha Rangaswamy, Rajeswaran Thiagesan, Sheela Auguesteen, Netty Kamp

Open access · diamondAbstract readEvaluation Study
In one paragraph

Article in Global health, science and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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  13. Implementation of a tuberculosis elimination project, India 2018-2019.Bulletin of the World Health Organization · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Ramya AnanthakrishnanREACH (Resource Group for Education and Advocacy for Community Health), Chennai, Tamil Nadu, India.
M D'Arcy RichardsonKNCV Tuberculosis Foundation, The Hague, Netherlands. Now an independent consultant, San Francisco, CA, USA.
Susan van den HofKNCV Tuberculosis Foundation, The Hague, Netherlands. Now with the National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Radha RangaswamyREACH (Resource Group for Education and Advocacy for Community Health), Chennai, Tamil Nadu, India.
Rajeswaran ThiagesanREACH (Resource Group for Education and Advocacy for Community Health), Chennai, Tamil Nadu, India.
Sheela AuguesteenREACH (Resource Group for Education and Advocacy for Community Health), Chennai, Tamil Nadu, India.
Netty KampKNCV Tuberculosis Foundation, The Hague, Netherlands. netty.kamp@kncvtbc.org.
Research for Equity And Community Health Trust · MW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrivate physicians in India see and treat more than half of all people with tuberculosis (TB) each year and thus have potential to make significant contributions to TB control. The EQUIP project was designed as a prospective cohort study to assess the potential of private providers to diagnose and appropriately treat drug-resistant TB (DR-TB) in the Central and South districts of Chennai, India.

methodsThe private-sector engagement model consisted of free access to rapid diagnostics; choice of free daily or thrice-weekly treatment regimens; support for notification of patients; and patient support including directly observed therapy through EQUIP centers staffed by a community-based interface agency. Data were collected on provider participation; referral results; treatment regimens prescribed; and treatment outcomes.

resultsFrom October 2015 through June 2017, 227 of the 466 (48.7%) private providers approached referred at least 1 patient to an EQUIP center for evaluation. A total of 2,621 patients received testing and 1,232 (47.0%) were diagnosed with TB. Of those, 727 (59.0%) were bacteriologically confirmed, including 694 (56.3%) using GeneXpert and 33 (2.7%) using smear microscopy. A total of 26 (3.7% of GeneXpert diagnosed) patients were confirmed as rifampicin-resistant cases. EQUIP-related notifications comprised approximately 10% of TB and DR-TB notifications in Chennai during the project period. The project initiated 1,167 (96.8%) drug-sensitive TB patients on treatment. Of those, 691 (59.2%) received standard daily regimens with EQUIP support and 288 (24.7%) received standard intermittent regimens. At the time of writing, 89.4% of 868 drug-susceptible TB patients receiving EQUIP support had treatment success. Of the 26 rifampicin-resistant TB cases notified, 20 (77%) started and continued on second-line treatment; 2 died and 4 were lost to follow-up prior to treatment initiation.

conclusionPrivate providers can make a substantial contribution to detection and appropriate treatment of patients with TB and DR-TB in India when provided with access to rapid diagnostics, support for notification and patient treatment through interface agencies, and free, quality anti-TB drugs.

Indexed as

Drug Resistance, MultiplePhysiciansPrivate PracticeProgram EvaluationPublic-Private Sector PartnershipsCommunicationDiagnostic ServicesDisclosureHumansIndiaPrivate SectorProspective StudiesPublic HealthQuality ImprovementReferral and ConsultationRifampinRifampin

Identifiers

PMID30926737
PMCPMC6538134
OpenAlexW2933178975

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.