Evidence map›Paper›PMID 30926717›Full record

ArticlePostgraduate medical journal2019

Low detection rate of advanced neoplasia within 5 years after polypectomy of small serrated adenoma.

Duochen Jin, Hailong Cao, Bikash Kumar Shah, Danfeng Chen, Yujie Zhang, Tianyu Liu, Wenxiao Dong, Sinan Wang, Yanrong Qi, Bangmao Wang

Open access · hybridAbstract read
In one paragraph

Article in Postgraduate medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Duochen JinDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.ORCID http://orcid.org/0000-0003-2385-9953
Hailong CaoDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China caohailong@tmu.edu.cn.
Bikash Kumar ShahDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.
Danfeng ChenDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.
Yujie ZhangDepartment of Pathology, General Hospital, Tianjin Medical University, Tianjin, China.
Tianyu LiuDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.
Wenxiao DongDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.
Sinan WangDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.
Yanrong QiDepartment of Gastroenterology and Hepatology, Tianjin Binhai People's Hospital, Tianjin, China.
Bangmao WangDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.
Tianjin Medical University General Hospital · CNTianjin People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimPatients with small serrated adenomas (SAs) (<10 mm) often undergo surveillance colonoscopy before the routine recommended time. We aimed to determine the appropriate surveillance intervals following polypectomy of small SAs for symptomatic patients.

methodWe retrospectively reviewed the data of 638 patients, including 122 cases and 516 controls. Subjects in the case group had small SAs at baseline colonoscopy, including sessile SA/polyps and traditional SAs, while subjects in the control group had negative findings. All patients underwent at least one surveillance colonoscopy during the following 5 years.

resultsThere was no significant difference in the incidence rate of advanced neoplasia between the two groups over a 5-year duration (3.6% vs 2.6%, p=0.455). Moreover, both groups also showed a low prevalence of SA formation over 1-5 years (3.6% vs 1.0%, p=0.145). Patients with baseline SA tended to undergo the first surveillance colonoscopy earlier than those without adenoma (≤1 year vs 1 to ≤3 years). Seventy-one (11.1%) of the total included subjects underwent inadequate initial colonoscopy, and 30 (42.3%) underwent early surveillance of adenoma formation within 1 year. Patients with a family history of colorectal cancer (OR 4.69, 95% CI 1.48 to 14.71, p=0.017) or inadequate baseline colonoscopy (OR 3.17, 95% CI 1.202 to 8.409, p=0.035) were at a higher risk of metachronous adenoma formation during the surveillance period.

conclusionPatients with small SAs at baseline gain little benefit from follow-up of colonoscopy within 5 years after complete polypectomy.

Indexed as

ColonoscopyAdenomaBiopsyColorectal NeoplasmsFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTime Factorsadvanced neoplasiacolonoscopypolypectomySerrated adenomasurveillance

Identifiers

PMID30926717
PMCPMC6585282
OpenAlexW2926292414

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.