Evidence map›Paper›PMID 30926571›Full record

Trial reportJournal of the American Academy of Child and Adolescent Psychiatry2019

Home Visiting and Antenatal Depression Affect the Quality of Mother and Child Interactions in South Africa.

Joan Christodoulou, Mary Jane Rotheram-Borus, Alexandra K Bradley, Mark Tomlinson

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the American Academy of Child and Adolescent Psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00972699 phase2completednot on this map

Mentor Mothers: A Sustainable Family Intervention in South African Townships

TypeinterventionalSponsorUniversity of California, Los AngelesRan2008 to 2011Enrolled1,200ConditionsHuman Immunodeficiency Virus, Acquired Immune Deficiency Syndrome, TuberculosisArmsPeer support and mentoring
NCT00995592 phase2completednot on this map

Philani Home-based Nutrition Intervention Program

TypeinterventionalSponsorUniversity of California, Los AngelesRan2002 to 2005Enrolled684ConditionsChild WeightArmsPhilani nutrition intervention program (mentor mothers)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  7. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Joan ChristodoulouSemel Institute, University of California-Los Angeles. Electronic address: jchristodoulou@mednet.ucla.edu.
Mary Jane Rotheram-BorusSemel Institute, University of California-Los Angeles.
Alexandra K BradleyInstitute for Life Course Health Research, Stellenbosch University, Stellenbosch, South Africa.
Mark TomlinsonInstitute for Life Course Health Research, Stellenbosch University, Stellenbosch, South Africa; School of Nursing and Midwifery, Queens University, Belfast, UK.

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KITCHEN, SCOTT G · 1991 to 2018
$39.9M
Neighborhood Alcohol & HIV Prevention in South African TownshipsR01AA017104 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2007 to 2011
$3.8M
Post-doctoral HIV Research Training Program for HIV Combination PreventionT32MH109205 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2016 to 2020
$2.3M
NIAAA NIH HHS R01 AA017104NIAID NIH HHS P30 AI028697NIMH NIH HHS P30 MH058107NIMH NIH HHS T32 MH109205
6 · The paper itself

Abstract

objectiveTo examine whether maternal depressed mood at birth moderated the protective effect of a home-visiting intervention on the quality of caregiving for children growing up in a low- and middle-income country.

methodAlmost all pregnant mothers in 24 Cape Town neighborhoods were recruited into a cluster randomized controlled trial matched by neighborhoods to the Philani home-visiting condition (HVC) or the standard care condition (SC). At 3 years after birth, the quality of mother-child interactions between HVC and SC mothers with and without antenatal depressed mood was assessed in a representative subset by rating videotaped observations of mother-child interactions on 10 dimensions of caregiving.

resultsAs predicted, maternal depressed mood at birth moderated the effect of the HVC on the quality of mother-child interactions. Among nondepressed mothers, mothers and their children in the HVC scored significantly higher on 5 of the 10 dimensions of the maternal-child interaction scale than mothers in the SC: mothers exhibited more maternal sensitivity, talked more, had more harmonious interactions, and had children who paid more attention and exhibited more positive affect. However, being in the HVC did not significantly affect the mother-child interaction scores among mothers with depressed mood. Among HVC children, those with mothers with depressed mood showed significantly less positive affect and talked less with their mothers than children with nondepressed mothers. SC children with mothers with depressed mood were more responsive and paid attention to their mothers than children with nondepressed mothers.

conclusionHome visiting resulted in a better quality of caregiving for mothers without depressive symptoms. Future interventions need to specifically target maternal depression and positive mother-child interactions. CLINICAL TRIAL REGISTRATION INFORMATION: Mentor Mothers: A Sustainable Family Intervention in South African Townships; https://clinicaltrials.gov; NCT00972699; Philani Home-based Nutrition Intervention Program; https://clinicaltrials.gov; NCT00995592.

Indexed as

House CallsMother-Child RelationsAdultChildChild DevelopmentChild HealthCommunity Health WorkersDepressionFemaleHumansMaternal HealthMothersOutcome Assessment, Health CarePostpartum PeriodPregnancyPregnancy Complicationschildrendepressionhome visitingmother–child interactionmothers

Identifiers

PMID30926571
PMCPMC7316421

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.