Evidence map›Paper›PMID 30926439›Full record

ReviewAnaerobe2019

Terbium chloride influences Clostridium difficile spore germination.

Ritu Shrestha, Joseph A Sorg

Open access · greenAbstract readReview
In one paragraph

Review in Anaerobe, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Phenotypic analysis of variousApplied and environmental microbiology · 2025
    Article
  2. Article
  3. Emerging Diagnostics inInternational journal of molecular sciences · 2024
    Review
  4. The impact of YabG mutations onbioRxiv : the preprint server for biology · 2024
    Article
  5. Novel metal peroxide nanoboxes restrainBioengineering & translational medicine · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Reuterin disruptsGut microbes · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ritu ShresthaDepartment of Biology, Texas A&M University, College Station, TX, 77843, USA.
Joseph A SorgDepartment of Biology, Texas A&M University, College Station, TX, 77843, USA. Electronic address: jsorg@bio.tamu.edu.
Texas A&M University · US

Funding

Decoding Antibiotic-induced Susceptibility to Clostridium difficile InfectionU01AI124290 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BRITTON, ROBERT A, GAREY, KEVIN W · 2016 to 2020
$7.9M
Mechanisms of Clostridium difficile spore germinationR01AI116895 · NIAID · TEXAS A&M UNIVERSITY · PI SORG, JOE · 2015 to 2024
$3.9M
NIAID NIH HHS R01 AI116895NIAID NIH HHS U01 AI124290
6 · The paper itself

Abstract

The germination of Clostridium difficile spores is an important stage of the C. difficile life cycle. In other endospore-forming bacteria, the composition of the medium in which the spores are generated influences the abundance of germination-specific proteins, thereby influencing the sensitivity of the spores towards germinants. In C. difficile media composition on the spores has only been reported to influence the number of spores produced. One of the measures of spore germination is the analysis of the release of DPA from the spore core. To detect DPA release in real time, terbium chloride is often added to the germination conditions because Tb

Indexed as

Clostridioides difficileCulture MediaFluorescenceGrowth SubstancesPicolinic AcidsSpores, BacterialStaining and LabelingTerbiumCulture Mediadipicolinic acidGrowth SubstancesPicolinic AcidsTerbiumterbium chlorideCalciumC. difficileClostridium difficileDipicolinic acidDPAEndosporeGerminationMagnesiumManganeseMetalsSporeTerbium

Identifiers

PMID30926439
PMCPMC6697597
OpenAlexW2925183627

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.