Evidence map›Paper›PMID 30925757›Full record

ArticleMolecules (Basel, Switzerland)2019

Curcumin and Resveratrol Regulate Intestinal Bacteria and Alleviate Intestinal Inflammation in Weaned Piglets.

Zhending Gan, Wenyao Wei, Yi Li, Jiamin Wu, Yongwei Zhao, Lili Zhang, Tian Wang, Xiang Zhong

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Review
  5. Article
  6. Article
  7. Review
  8. Impact of curcumin on gut microbiome.World journal of experimental medicine · 2025
    Review
  9. Article
  10. Article
  11. Curcumin Inhibits Oxidative Stress and Apoptosis Induced by HAnimals : an open access journal from MDPI · 2024
    Article
  12. Review
  13. Review
  14. Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhending GanNanjing Agricultural University, Nanjing 210000, China. 2017105067@njau.edu.cn.ORCID 0000-0002-6038-3184
Wenyao WeiNanjing Agricultural University, Nanjing 210000, China. w_wenyao@163.com.
Yi LiNanjing Agricultural University, Nanjing 210000, China. 2016105063@njau.edu.cn.
Jiamin WuNanjing Agricultural University, Nanjing 210000, China. 2018105066@njau.edu.cn.
Yongwei ZhaoNanjing Agricultural University, Nanjing 210000, China. yanninuist@163.com.
Lili ZhangNanjing Agricultural University, Nanjing 210000, China. zhanglili@njau.edu.cn.
Tian WangNanjing Agricultural University, Nanjing 210000, China. tianwangnjau@163.com.
Xiang ZhongNanjing Agricultural University, Nanjing 210000, China. zhongxiang@njau.edu.cn.ORCID 0000-0002-8622-8078
Nanjing Agricultural University · CN

Funding

National Natural Science Foundation of China NO. 31872391Natural Science Foundation of Jiangsu province NO. BK 20161446
6 · The paper itself

Abstract

Human infants or piglets are vulnerable to intestinal microbe-caused disorders and inflammation due to their rapidly changing gut microbiota and immaturity of their immune systems at weaning. Resveratrol and curcumin have significant anti-inflammatory, bacteria-regulating and immune-promoting effects. The purpose of this study was to investigate whether dietary supplementation with resveratrol and curcumin can change the intestinal microbiota and alleviate intestinal inflammation induced by weaning in piglets. One hundred eighty piglets weaned at 21 ± 2 d were fed a control diet (CON group) or supplemented diet (300 mg/kg of antibiotics, ANT group; 300 mg/kg of resveratrol and curcumin, respectively, HRC group; 100 mg/kg of resveratrol and curcumin, respectively, LRC group; 300 mg/kg of resveratrol, RES group; 300 mg/kg of curcumin, CUR group) for 28 days. The results showed that compared with the CON group, curcumin alone and antibiotics decreased the copy numbers of

Indexed as

WeaningAnimalsAnti-Bacterial AgentsBacteriaBiodiversityCurcuminDietDietary SupplementsFemaleGastrointestinal MicrobiomeImmunoglobulinsInflammationInterleukinsMaleResveratrolRNA, MessengerAnti-Bacterial AgentsCurcuminImmunoglobulinsInterleukinsResveratrolRNA, MessengerToll-Like Receptor 4curcuminintestinal bacteriaintestinal inflammatoryresveratroltoll-like-receptor 4weaned piglets

Identifiers

PMID30925757
PMCPMC6479679
OpenAlexW2924144420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.